Engaging large numbers of undergraduates in authentic scientific discovery is desirable but difficult to achieve. We have developed a general model in which faculty and teaching assistants from diverse academic institutions are trained to teach a research course for first-year undergraduate students focused on bacteriophage discovery and genomics. The course is situated within a broader scientific context aimed at understanding viral diversity, such that faculty and students are collaborators with established researchers in the field. The Howard Hughes Medical Institute (HHMI) Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) course has been widely implemented and has been taken by over 4,800 students at 73 institutions. We show here that this alliance-sourced model not only substantially advances the field of phage genomics but also stimulates students’ interest in science, positively influences academic achievement, and enhances persistence in science, technology, engineering, and mathematics (STEM) disciplines. Broad application of this model by integrating other research areas with large numbers of early-career undergraduate students has the potential to be transformative in science education and research training.

Numerous national reports have called for reforming laboratory courses so that all students experience the research process. In response, many course-based research experiences (CREs) have been developed and implemented. Research on the impact of these CREs suggests that student benefits can be similar to those of traditional apprentice-model research experiences. However, most assessments of CREs have been in individual courses at individual institutions or across institutions using the same CRE model. Furthermore, which structures and components of CREs result in the greatest student gains is unknown. We explored the impact of different CRE models in different contexts on student self-reported gains in understanding, skills, and professional development using the Classroom Undergraduate Research Experience (CURE) survey. Our analysis included 49 courses developed and taught at seven diverse institutions. Overall, students reported greater gains for all benefits when compared with the reported national means for the Survey of Undergraduate Research Experiences (SURE). Two aspects of these CREs were associated with greater student gains: 1) CREs that were the focus of the entire course or that more fully integrated modules within a traditional laboratory and 2) CREs that had a higher degree of student input and results that were unknown to both students and faculty.

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Developing visual literacy skills is an important component of scientific literacy in undergraduate science education. Comprehension, analysis, and interpretation are parts of visual literacy that describe related data analysis skills important for learning in the biological sciences. The Molecular Biology Data Analysis Test (MBDAT) was developed to measure students’ data analysis skills connected with scientific reasoning when analyzing and interpreting scientific data generated from experimental research. The skills analyzed included basic skills, such as identification of patterns and trends in data and connecting a method that generated the data, and advanced skills, such as distinguishing positive and negative controls, synthesizing conclusions, determining if data supports a hypothesis, and predicting alternative or next-step experiments. Construct and content validity were established and calculated statistical parameters demonstrate that the MBDAT is valid and reliable for measuring students’ data analysis skills in molecular and cell biology contexts. The instrument also measures students’ perceived confidence in their data interpretation abilities. As scientific research continues to evolve in complexity, interpretation of scientific information in visual formats will continue to be an important component of scientific literacy. Thus science education will need to support and assess students’ development of these skills as part of students’ scientific training.

As college educators, our main teaching goals are to increase student learning and improve student retention.  This study describes how 54 science majors at a public, minority serv- ing institution reflected on their study time, study activities, and overall grade motivation in a core-curriculum introduc- tory biology course.  Since 2005, less than 50% of students enrolled in this course at our university earned a final grade of “C” or better.  In the Fall semester of 2009, we adminis- tered a pre and post assessment using the Science Motivation Questionnaire (SMQ) a 30-item Likert-type instrument devel- oped by Glynn and Koballa (2006) to better understand and address the student attrition from the introductory biology course.  All 30 items from the SMQ were analyzed, but only 5 items relevant to grade motivation are presented in this paper.  We also designed and implemented a weekly study log assessment tool for students to document their study time and study activities, wherein students submitted their study logs on a weekly basis during the course of this research study.   Based on the number of study logs submitted and study time by each student, students were classified into ei- ther a high-metacognition or low-metacognition group.  For our purposes, we defined metacognition as the awareness of one’s own thinking process (Merriam-Webster, 2012). The high-metacognition group submitted 75% of their study logs and earned a grade in the top 25% of the class.   The low- metacognition group submitted only 25% of their study logs and earned a grade in the bottom 25% of the class.   Thus both groups formed reasonable expectations for their overall class performance.