Hierarchical analysis refers to the method of dividing the elements related to the result into different levels such as goals, methods, and processes and then performing quantitative and qualitative analysis according to different levels. It can hierarchize complex methods and make the solution process more scientific and reasonable. High-performance computing refers to computing systems and environments that usually use many processors or several computers organized in a cluster. In fact, there are many different types of high-performance computing systems on the market, most of which are used in conjunction with the network. For example, Ford built an online market with high-performance computers and connected to its more than 30,000 suppliers through the network. This kind of online procurement can not only lower prices and reduce procurement costs, but also shorten the procurement time. Ford estimates that this can save approximately $8 billion in procurement costs. In addition, fields such as manufacturing, logistics, and market research are also areas where high-performance computers show their talents. This article aims to study the analysis and evaluation of multitone piano transcription that rely on hierarchical analysis high-performance computing algorithms and hopes to use high-performance computing algorithms to make piano recordings more harmonious. This paper proposes a differential variable-multivariate curve resolution for accurate analysis of GC-MS overlapping peaks, mainly to solve the problem of inaccurate results caused by the difficulty in determining the components during the analysis of overlapping peaks; carrying out matrix calculation on the piano tone characteristic matrix, it realizes the electronic synthesis of the 25th harmonic of the piano tone. The experimental results in this paper show that when the number of Gaussians in the recording process becomes 5, the gap between the sound pressure amplitude and the sound pressure phase is significantly reduced; when the number of Gaussians is 10, the value of the sound pressure phase has an overshoot phenomenon; when the number of Gaussians is 15, the difference between the sound pressure amplitude and the sound pressure phase is the smallest, indicating that the error at this time is the smallest, and it is the most ideal recording environment.