No abstract

Plants have evolved an array of adaptive responses to low Pi availability, a process modulated by various external stimuli and endogenous growth regulatory signals. Little is known about how these signaling processes interact to produce an integrated response. () encodes a conserved MYB-type transcription factor that is essential for programming Pi starvation-induced gene expression and downstream Pi starvation responses (PSRs). Here, we show that loss-of-function mutations in and, encoding two positive regulators of phytochrome signaling, and in , encoding a master regulator of ethylene responses, cause attenuated expression, whereas mutation in , encoding another positive regulator of light signaling, causes increased expression. FHY3, FAR1, HY5, and EIN3 directly bind to the promoter through distinct-elements. FHY3, FAR1, and EIN3 activate, while HY5 represses, expression. FHY3 directly interacts with EIN3, and HY5 suppresses the transcriptional activation activity of FHY3 and EIN3 on Finally, both light and ethylene promote FHY3 protein accumulation, and ethylene blocks the light-promoted stabilization of HY5. Our results suggest that light and ethylene coordinately regulate expression and PSRs through signaling convergence at the promoter.

No abstract

Puerarin-dendrimer complexes represent a potential ocular drug delivery system to improve the efficacy of drug treatment.