Abstract. We present images of the SNR HB3 at both 408 MHz and 1420 MHz from the Canadian Galactic Plane Survey mainly based on data from the Synthesis Telescope of the Dominion Radio Astrophysical Observatory. We reproduce the 100 m-Effelsberg HB3 image at 2695 MHz at large scale, and find that there exists a background emission gradient across the HB3 area. Based on our analysis of background emission and the boundary between W3 and HB3, we give HB3's flux density as 68.6 ± 11.5 Jy at 408 MHz and 44.8 ± 12.0 Jy at 1420 MHz, after subtracting flux from compact sources within HB3. The integrated flux-density-based spectral index between 408 MHz and 1420 MHz is 0.34 ± 0.15. The averaged T-T plot spectral index using all subareas is 0.36. Our measurement values are less than a previously published value of 0.6. The 408-1420 MHz spectral index varies spatially in HB3 in the range 0.1 to 0.7. We investigate the data used by previous authors, and consider more data at 232 MHz, 3650 MHz and 3900 MHz which are not included in previous calculations. There is evidence for two spectral indices for HB3 in the radio band, i.e., 0.63 (38-610 MHz) and 0.32 (408-3900 MHz). This is consistent with the spatial variations: the low frequency data mainly reflects the steeper indices and the high frequency data mainly reflects the flatter indices.

Poliovirus genomic RNA replication, protein translation, and virion assembly are performed in the cytoplasm of host cells. However, this does not mean that there is no relationship between poliovirus infection and the cellular nucleus. In this study, recombinant fluorescence-tagged poliovirus 3CD and 3C 0 proteins were shown to be expressed mainly in the cytoplasm of Vero cells in the absence of other viral proteins. However, upon poliovirus infection, many of these proteins redistributed to the nucleus, as well as to the cytoplasm. A series of transfection experiments revealed that the poliovirus 2A pro was responsible for the same redistribution of 3CD and 3C 0 proteins to the nucleus. Furthermore, a mutant 2A pro protein lacking protease activity abrogated this effect. The poliovirus 2A pro protein was also found to co-localize with the Nup153 protein, a component of the nuclear pore complexes on the nuclear envelope. These data provide further evidence that there are intrinsic interactions between poliovirus proteins and the cell nucleus, despite that many processes in the poliovirus replication cycle occur in the cytoplasm.

A precise transit ephemeris serves as the premise for follow-up exoplanet observations. We compare TESS Object of Interest (TOI) transit timings of 262 hot Jupiters with the archival ephemeris and find 31 of them having TOI timing offsets, among which WASP-161b shows the most significant offset of −203.7 ± 4.1 minutes. The median value of these offsets is 17.8 minutes, equivalent to 3.6σ. We generate TESS timings in each sector for these 31 hot Jupiters, using a self-generated pipeline. The pipeline performs photometric measurements to TESS images and produces transit timings by fitting the light curves. We refine and update the previous ephemeris, based on these TESS timings (uncertainty ∼1 minute) and a long timing baseline (∼10 yr). Our refined ephemeris gives the transit timing at a median precision of 0.82 minutes until 2025 and 1.21 minutes until 2030. We regard the timing offsets to mainly originate from the underestimated ephemeris uncertainty. All the targets with timing offset larger than 10σ present earlier timings than the prediction, which cannot be due to underestimated ephemeris uncertainty, apsidal precision, or Rømer effect as those effects should be unsigned. For some particular targets, timing offsets are likely due to tidal dissipation. Our sample leads to the detection of period-decaying candidates of WASP-161b and XO-3b reported previously.

Supernovae are extremely luminous and can outshine an entire galaxy for a period of days. Two main physical mechanisms are used to explain supernova explosions: thermonuclear explosion of a white dwarf (Type Ia) and core collapse of a massive star (Type II and Type Ib/Ic). Type Ia supernovae serve as distance indicators that led to the discovery of the accelerating expansion of the Universe. The exact nature of their progenitor systems however remain unclear. Radio emission from the interaction between the explosion shock front and its surrounding circumstellar medium (CSM) or interstellar medium (ISM) provides an important probe into the progenitor star's last evolutionary stage. No radio emission has yet been detected from Type Ia supernovae by current telescopes. The SKA will hopefully detect radio emission from Type Ia supernovae due to its much better sensitivity and resolution. There is a 'supernovae rate problem' for the core collapse supernovae because the optically dim ones are missed due to being intrinsically faint and/or due to dust obscuration. A number of dust-enshrouded optically hidden supernovae should be discovered via SKA1-MID/survey, especially for those located in the innermost regions of their host galaxies. Meanwhile, the detection of intrinsically dim SNe will also benefit from SKA1. The detection rate will provide unique information about the current star formation rate and the initial mass function. A supernova explosion triggers a shock wave which expels and heats the surrounding CSM and ISM, and forms a supernova remnant (SNR). It is expected that more SNRs will be discovered by the SKA. This may decrease the discrepancy between the expected and observed numbers of SNRs. Several SNRs have been confirmed to accelerate protons, the main component of cosmic rays, to very high energy by their shocks. This brings us hope of solving the Galactic cosmic ray origin's puzzle by combining the low frequency (SKA) and very high frequency (Cherenkov Telescope Array: CTA) bands' observations of SNRs.Advancing Astrophysics with the Square Kilometre Array

Very-High Energy (VHE) gamma-ray astroparticle physics is a relatively young field, and observations over the past decade have surprisingly revealed almost two hundred VHE emitters which appear to act as cosmic particle accelerators. These sources are an important component of the Universe, influencing the evolution of stars and galaxies. At the same time, they also act as a probe of physics in the most extreme environments known -such as in supernova explosions, and around or after the merging of black holes and neutron stars. However, the existing experiments have provided exciting glimpses, but often falling short of supplying the full answer. A deeper understanding of the TeV sky requires a significant improvement in sensitivity at TeV energies, a wider energy coverage from tens of GeV to hundreds of TeV and a much better angular and energy resolution with respect to the currently running facilities. The next generation gamma-ray observatory, the Cherenkov Telescope Array Observatory (CTAO), is the answer to this need. In this talk I will present this upcoming observatory from its design to the construction, and its potential science exploitation. CTAO will allow the entire astronomical community to explore a new discovery space that will likely lead to paradigm-changing breakthroughs. In particular, CTA has an unprecedented sensitivity to short (sub-minute) timescale phenomena, placing it as a key instrument in the future of multi-messenger and multi-wavelength time domain astronomy. I will conclude the talk presenting the first scientific results obtained by the LST-1, the prototype of one CTA telescope type -the Large Sized Telescope, that is currently under commission.