Objective: Evaluation of children's quality of life (QoL) after finished brain tumour treatment and the association of children's diseases on quality of their parents' life.Methods: The study group was consisted of 46 children after brain tumour treatment (aged 4, 5, to 29 years old). The control group was composed of 104 students of primary, secondary, and high schools. One hundred fifty (104 + 46) parents were included in the study. Standardised QoL questionnaires (PEDsQL-4.0, WHOQOL-BREF) were used. Survivors' QoL was assessed from patients' and their parents' point of view, also the association of children's diseases on quality of their parents' life was estimated.Results: QoL of children after brain tumour treatment was lower than in the control group according to the children (P < 0.001) and their parents (P < 0.001). The survivors worst rated their ability to social functioning (P < 0.0010) and physical functioning (P < 0.001) in comparison with self-assessment of healthy children. According to their parents, the functioning of children in all zones was worse than in the control group, mostly in social (P < 0.001) and physical sphere (P < 0.001), too. QoL of children with low-grade tumour was comparable with QoL of children with high-grade tumour).QoL of survivors' caregivers in study was higher than QoL of parents of control groups (P = 0.023). Conclusions:The quality of patients' life after brain tumour treatment is lower in comparison with healthy children. QoL of the parents of survivor is higher than the QoL of healthy children parents. The assessment of QoL of children after brain tumour treatment should be an inherent element of health monitoring. KEYWORDS brain tumour, children, cancer, oncology, quality of life 1 | BACKGROUND Central nervous system (CNS) tumours are the second most common group of cancers in children, accounting for a more than quarter (26%) of all childhood cancers. 1 Their reported incidence has been increasing over the past 30 years, probably due to improved diagnostics. Composed anticancer therapy usually involves at least one of three main modalities: localised surgical resection, radiotherapy, and/or chemotherapy. 2 Refinements in imaging, surgical technique, and adjunctive therapies have led to longer survival in children with CNS tumours. 3 Over the years, a 5-year survival rate for childhood CNS tumours increased, currently up to 72% owing to the introduction and ongoing modification of powerful treatment protocols. 4Aggressive treatment is often essential to cure this potentially lethal

Background:Mental disorders require a comprehensive and specialized psychiatric and psychological assistance, so it is necessary to evaluate patients' mental state with specialized tools. The usability of Barratt Impulsiveness Scale and Liebowitz Social Anxiety Scale and their correlation with the Beck Depression Inventory to determine the mental state of the patient.Subjects and Methods:The study included 67 patients. The study group had 30 patients treated in open ward of the Department of Psychiatry and Psychotherapy GCM SUM throughout 11/2012-03/2013. The control group included 37 patients without mental disorders. Three questionnaires were used: Beck, Barratt and Liebowitz.Results:Analyzed groups had significant differences in terms of Beck Scale (U Mann-Whitney test p=0.000001).) Average score in study group: 22.8+/-12.8 median 22; in control group: 7.51+/-6.7 median 6. Groups had significant differences in terms of Liebowitz Scale (U test Mann- Whitney test, p = 0.0067). Average score in study group: 56.8+/- 29.3 median 57; in control group: 37.2+/-26.2 median 28. Groups had significant differences in terms of Barratt Scale (t-student test p=0.001). Average in study group: 66.7+/-10 median 67; in control group: 59.1+/-8.2 median 58. Significant positive correlation was observed between the results of Beck Scale and Liebowitz Scale (r = 0.602289).Conclusions:The intensity of the Liebowitz Social Anxiety is directly proportional to the severity of depression according to Beck. The degree of impulsivity with Barrat scale does not correlate with the level of depression according to Beck scale.