Background: Subarachnoid Hemorrhage (SAH) , is hemorrhage into the subarachnoid space the space between the arachnoid membrane and pia membrane around the brain symptoms may include a severe headache vomiting, decreased level of consciousness, fever, and seizures. Aim: This study aimed to test the effect of an educational program on nurses` performance regarding care for patients with subarachnoid hemorrhage. Design: A quasiexperimental design was utilized to conduct this study. Setting: This study was conducted in the neurology unit at Benha University hospitals. Subject: A convenience sample (60) nurses working in neurology unit at Benha University hospitals. Tools: two tools were used in this study; structured interview questionnaire sheet, and observational checklist sheet to evaluate nurses' practice regarding care for patients with subarachnoid hemorrhage. Results: 50% of the nurses under the study were aged 20-30 years old, 66.7% of them were female, 66% of the studied nurses had satisfactory level of knowledge preprogram compared 95% of them had satisfactory level of knowledge post program and 91.6% in follow up, 26.6% of them had good level of practice preprogram compared with 73.3% of them had good level of practice post program and descend to 51.6% of them had good level of practice in follow up. Conclusion: There is positive correlation between nurses` information and skills regarding care for patients with subarachnoid hemorrhage post program. Implementation of educational program has a positive effect on improvement of the nurses` knowledge and practice regarding care for patients with subarachnoid hemorrhage post program than preprogram. Recommendation: Continuous evaluation of nurses' knowledge and practice is essential to identify nurses' needs for implementing educational program regarding care for patient with subarachnoid hemorrhage.