Despite the limited number of large clinical trials on the positive therapeutic effect of medical marijuana, the several thousand-year history of using cannabis in medicine and numerous reports allow the conclusion that cannabis preparations have a great therapeutic potential. The report presents the clinical case of a 35-year-old female patient treated with medical marijuana preparations due to persistent headache following neurosurgical resection of a brain tumour. Therapy with medical marijuana was started 3 years after surgery. Headache occurred several times a day and responded poorly to NSAIDs, which resulted in the patient often giving-up pharmacological treatment. The applied treatment with dried cannabis with high THC content taken by vaporization in a finally dose of 0.1 g twice a day showed a significant reduction in pain by 7-9 on the NRS within the 3 months of therapy. This observation suggests a significant analgesic effect of cannabis in the treatment of symptomatic headaches.

Aesthetic medicine offers a very wide range of beauty treatments. However, most of the filling substances (e.g. hyaluronic acid, calcium hydroxyapatite, polylactic acid) are absorbed with time and thus require replenishment. Treatments should be repeated at different time intervals. Moreover, such treatments depend on the intra-tissue administration of different substances that improve the appearance and exert rejuvenating effects albeit are simply foreign bodies. Alternatively, the patient`s fat can be used as a filling substance. Autologous adipose tissue transplants are called lipofilling. The method is extremely safe as the patient's own tissue is transplanted, which eliminates the risk of rejection. In other procedures with fillers, the substances used are foreign materials and generate the risk of inflammatory conditions. Therefore, an ideal alternative is to use the patient's fat for filling, i.e. adipose tissue autotransplantation. The tissue needed for the procedure, is obtained by excision or liposuction of the adipose tissue from fat deposits using cannulas. Subsequently, the collected material is centrifuged, decanted and injected into the area requiring correction. Noteworthy, in aesthetic and cosmetic medicine, the fatty tissue is considered a free transplant that has to be incorporated into the surrounding tissues (the affected area) and therefore, the volume of fat transplanted during one procedure cannot be large. Nevertheless, it is a living tissue, which will live normally and remain permanently in the new area. Fat transplants reduce wrinkles that appear with age, stimulate, rejuvenate, smooth the skin and correct various asymmetries and defects, which improves the skin tonicity and significantly enhances microcirculation; thus, the skin becomes well-toned, youthful and much smoother. The use of the patient's own tissue causes no allergic reactions and no risk of rejection. Such a transplant does not lead to any inflammatory reactions around the transplanted fat tissue.