Gaceta Mexicana de Oncologia. 2017;16(3):207-211 Resumen Introducción: El melanoma metastásico al páncreas fue descrito por primera vez en 1931. Las metástasis pancreáticas se presentan con frecuencia en los pacientes con enfermedad difusa, la metástasis única es bastante rara; el papel de metastasectomía pancreática en pacientes con melanoma maligno no está definido en la actualidad debido a que existen muy pocos reportes disponibles. Caso clínico: Se revisa el caso de un paciente de sexo masculino de 54 años con historia de melanoma maligno nodular en muslo izquierdo EC IIIC en el que después de 11 meses de seguimiento se detecta una lesión metastásica única en cabeza de páncreas: Para mejorar nuestra comprensión de estas lesiones se describe un caso tratado con resección pancreática en nuestro hospital. Aquí, se discuten las características clínicas de su presentación, tratamiento y seguimiento junto con una revisión de la literatura. Discusión: La mayoría de los autores recomiendan la cirugía como el tratamiento de elección para las metástasis pancreáticas que son susceptibles de resección, ya que parece ser el único tratamiento capaz de prolongar la supervivencia, aunque no existen estudios grandes que demuestren totalmente este supuesto. Conclusión: Esta revisión sugiere que en un paciente con características tumorales favorables, la cirugía debe ser considerada como una opción viable de tratamiento y es necesario realizar estudios con mayor número de pacientes. (creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Introduction: Metastatic melanoma to the pancreas was first described in 1931. Pancreatic metastases occur frequently in patients with diffuse disease, solitary metastasis is quite rare; currently, the role of pancreatic metastasectomy in patients with malignant melanoma is not defined because there are very few reports available. Case report: The case of a male patient aged 54 with a history of nodular malignant melanoma left thigh EC IIIC, in PALABRAS CLAVESMelanoma maligno cutáneo; Pancreatoduodenectomia; Inmunoterapia KEY WORDSCutaneous malignant melanoma;
Metastatic melanoma to the pancreas was first described in 1931. Pancreatic metastasis occurs commonly in patients with diffuse disease with solitary metastasis being quite rare. The role of pancreatic metastasectomy in patients with malignant melanoma is currently not defined because there are very few available reports. The case is reviewed of a 54-yearold male patient with a history of left thigh Stage IIIC malignant nodular melanoma. After 11-month follow-up, a single metastasis to the head of the pancreas was detected. To improve our understanding on these lesions, a case treated with pancreatic resection in our hospital is described. Here, clinical features of presentation, treatment and follow-up are discussed, along with a literature review. Most authors recommend surgery as the treatment of choice for pancreatic metastases that are amenable to resection since it appears to be the only treatment able to prolong survival, although there are no large studies fully demonstrating this assumption. This review suggests that, in a patient with favorable tumor characteristics, surgery should be considered a viable treatment option, but studies have to be conducted with larger numbers of patients. (creativecommons.org/licenses/by-nc-nd/4.0/).
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