The Empore disk biomimetic extraction procedure is a
method to estimate total body residues (TBR
est) in biota
after exposure to complex mixtures of organic chemicals
in water. Except for highly hydrophobic compounds, the
extraction procedure is nondepletive by using an excess of
water. Therefore, it is a selective extraction process of
the bioavailable fraction of compounds. The extent, to which
compounds are extracted, depends on their hydrophobicity.
Consequently, compounds that only have a minor
contribution to the total amount in exhaustive extracts
can become very prominent in the biomimetic extracts.
Bioconcentration is also a process that depends primarily
on hydrophobicity. In this study the method is applied to
selectively focus on compounds with a high bioconcentration
potential. This feature is illustrated by data on two
fragrances (HHCB and AHTN) in effluents of municipal
sewage treatment plants and several types of surface water.
Although estimated aqueous concentrations of both
AHTN and HHCB ranged from about only 1 ng/L in clean
surface water to 500 ng/L in the effluents of sewage treatment
plants, the contribution of these two compounds together
to the total amount of extracted compounds varied
from 1 to 23% for surface waters and from 5 to 22% for
effluents.
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