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Excavations in 1964 at the Pine Spring site in southwest Wyoming concluded that the site contains three cultural occupation levels; the earliest allegedly dates to the terminal Pleistocene and is associated with megafauna. However, excavations in 1998 and 2000, and analysis of the stratigraphy, AMS dates, micromorphology, and artifact carbonate isotopes, along with debitage refitting, density, orientation, inclination, burning, and trample damage, could not replicate the 1964 findings. A hiatus in deposition accounts for the highest density of artifacts, and the three original occupations are palimpsests. There is no unequivocal association between evidence of human activity and megafaunal remains.

Background Previous research from our group found that recent depressive symptoms were associated with 3-year change in carotid intima-media thickness (CA-IMT), a biomarker of cardiovascular disease risk, in an initially healthy sample of older adults. Trait measures of anxiety, anger, and hostility did not predict 3-year CA-IMT progression in that report. Purpose The current study sought to reexamine these associations at a 6-year follow-up point. Methods Two-hundred seventy-eight participants (151 males, mean age = 60.68 years) from the original sample completed an additional IMT reading 6 years following the initial baseline assessment. Results Though not significant at 3-years, trait-anger emerged as a predictor of IMT progression at the 6-year point. When examined in separate regression models, both depression and trait-anger (but not anxiety or hostility) predicted 6-year IMT change (b = .017, p = .002; b = .029, p = .01, respectively). When examined concurrently, both depression and anger were independently associated with 6-year IMT progression (b = .016, p = .010, b = .028, p = .022, respectively). Exploratory analyses suggest that the relative contributions of anger and depression may differ for males and females. Conclusions The use of sequential follow-ups is relatively unique in this literature, and our results suggest a need for further research on the timing and duration of psychosocial risk exposures in early stages of cardiovascular disease.

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