Careful studies of offenders make group-types stand out with distinctness. Very little advancement in the treatment of delinquents or criminals can be expected if typical characteristics and their bearings are not understood. The group that our present work concerns itself with is comparatively little known, although cases belonging to it, when met, attract much attention. It is to all who should be acquainted with these striking mental and moral vagaries, particularly in their forensic and psychological significances, that our essay is addressed. In some cases vital for the administration of justice, an understanding of the types of personality and of behavior here under discussion is a prime necessity. The whole study of characterology or the motivation of conduct is extremely new, and there are many indications of immense values in uncovered fields. Some appreciation of this fact may be gained from the following pages which show the possibility of tracing one form of behavior to its source. We have laid under contribution practically the entire literature on the subject, almost none of which is in English, and also the thorough-going longitudinal case studies made by the Juvenile Psychopathic Institute of Chicago. In the latter material there was found much of value bearing upon the subject of lying, false accusation, and swindling of pathological character. Our institute, later taken over officially by the Juvenile Court of Cook County, was for five years maintained upon a foundation provided by Mrs. W. F. Dummer.
Paraneoplastic pemphigus (PNP) is a rare syndrome driven by antibodies (IgG) binding to desmogleins and other epidermal proteins leading to skin erosions. In rare instances, these same IgG proteins may also target the bronchial mucosa leading to an irreversible fibrotic reaction within the epithelium and subsequent obstructive lung disease. A 51-year-old man presented to the emergency department with 2–3-month history of dyspnoea as well as oral and genital ulcerations and inguinal lymphadenopathy. The ulcerations were biopsied and proven to be consistent with pemphigus. Subsequent inguinal lymph node biopsy implicated the hyaline-vascular variant of Castleman's disease (CD), as the primary cause of the patient's pemphigus. The patient underwent pulmonary function testing that demonstrated severe airflow obstruction. The patient was diagnosed with PNP and associated bronchiolitis obliterans syndrome (BOS). He was treated with rituximab for his CD, and oral and inhaled corticosteroids along with azithromycin for his BOS.
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