Introduction:Madelung’s disease (MD) is a rare disorder of unknown etiology defined as the presence of multiple and symmetrical fatty accumulations most commonly involving the upper trunk, neck, and head. Excessive alcohol ingestion has been linked traditionally to the pathogenesis of the disease. The central and peripheral nervous system could both be affected. Presenile dementia, without alcohol abuse, has been rarely reported in the literature as a complication.Aim:The aim of this case report is to highlight that multiple symmetric lipomatosis can be complicated by presenile dementia even if the patient is non-alcoholic.Case Report:This case report describes a middle age non-alcoholic woman who presented for increased forgetfulness. Brain CT scan showed cerebral and cerebellar atrophy inappropriate for her age. Despite being started on anticholinergic drug, her MMSE decreased 3 points in 1 year.Conclusion:Clinicians should consider early onset dementia as a potential complication of Madelung’s disease even in patients with no preceding history of alcoholism. A brain MRI and MMSE can aid with identifying such a complication.
The Navy has outlined an aggressive weapon separation clearance program for the F/A-18E/F Super Hornet Engineering, Manufacturing, and Development (EMD) phase that encompasses 18 different stores and 33 unique weapons loadings, 27 of which were flight tested during EMD. This paper outlines the F/A-18E/F weapons separation flight test program including: the role of wind tunnel test data and analysis, store telemetry data, photogrammetric process and data, and comparisons of wind tunnel based analysis to flight test weapon trajectories and clearance distances. The results indicate that high fidelity wind tunnel testing can be used to structure a more cost effective and lower risk flight test program. Wind tunnel based trajectories and clearance distances compare quite well with the majority of flight test results throughout the flight envelope. The most difficult areas to correlate are stores with deployable or movable surfaces and releases in the high transonic region between Mach 0.9 and 1.0. Careful attention to modeling details greatly improves prediction capability in the transonic region.
Penile ossification, a rare condition, has been linked traditionally to Peyronie's disease (PD) despite the presence of other less common etiologies. The ossification takes place usually in the mid-shaft of the penis with few cases reporting involvement of the entire shaft. Ultrasound has been the method of choice to demonstrate plaque calcifications. Medical and surgical treatment options exist depending on the extent of ossification and symptoms. This case report discusses the presence of ossification in the entire penile shaft which has been found incidentally on a pelvic x-ray in a patient presenting to the emergency department for a trauma of the knee.
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