Background: Risky sexual behaviors are associated with the number of sexual partners, and non-use of condom, among other factors. Objective: To identify the profile of health students attending a higher education institution, according to demographic and sexual characteristics. Methods: This is a prospective, cross-sectional and descriptive study with a quantitative approach using a sample of 819 university health students. We used a questionnaire in order to obtain information on the students' demographic characteristics, sexual behaviors and knowledge of STIs/AIDS. We defined risky behavior as the adoption of 2 or more of the following sexual behaviors: non-use of condom, more than 10 sexual partners, sexual intercourse under the influence of alcohol/drugs, and sexual intercourse with little or recently known person. Results: The sample was composed of 77.41% (634) of women and 22.59% (185) of men, with a mean age of 24.4 years (SD ± 6.7). Most participants (52%) reported risky behaviors and insufficient knowledge of STIs. Conclusion: The fact that 52% of the participants reported risky sexual behaviors points to the need for preventive interventions among this population, aimed at raising awareness and reducing the risk of STIs.

Metformin was not effective in reducing BMI and preventing GDM in obese pregnant women.

Objective: To evaluate whether there is an association between altered maternal lipid profile and the lipid profile of the newborn in a maternity hospital. Subjects and method: Cross-sectional study with 435 parturients and their respective newborns. Blood samples from the newborns were collected during delivery by venipuncture of the umbilical cord close to the placenta. Blood samples from the parturients were collected in the pre-delivery room or right after delivery. The concentrations of total cholesterol, triglycerides and HDL-c were determined by an enzymatic colorimetric method and LDL-c was calculated by the Friedewald formula. Results: There was no significant difference in mean concentrations of total cholesterol, LDL-c, HDL-c and triglycerides in neonates according to altered or non-altered maternal total cholesterol, LDL-c, HDL-c and triglycerides. Conclusions: Change in maternal lipid profile is not significantly associated with the mean concentrations of total cholesterol, LDL-c, HDL-c and triglycerides in newborns. Arch Endocrinol Metab. 2015;59(2):123-8

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Objective: To evaluate the use of metformin for preventing cesarean deliveries and large-forgestational-age (LGA) newborn (NB) outcomes in non-diabetic obese pregnant women. Subjects and methods: This is a randomized clinical trial with obese pregnant women, divided into 2 groups: metformin group and control group, with followed-up prenatal routine. The gestational age of participants was less than or equal to 20 weeks and were monitored throughout entire prenatal period. For outcomes of delivery and LGA newborns, absolute risk reduction (ARR) and the number needed to treat (NNT) were calculated with a 95% confidence interval (CI). Results: 357 pregnant women were evaluated. From the metformin group (n = 171), 68 (39.8%) subjects underwent cesarean delivery, and 117 (62.9%) subjects from the control group (n = 186) had intercurrence (p < 0.01). As for the mothers' general characteristics, there was significance for marital status (p < 0.01). Maternalfetal results presented reduced preeclampsia (p < 0,01). Primary prophylactic results presented an ARR of 23.1 times (95% CI: 13.0-33.4) with NNT of 4 (95% CI: 3.0-7.7) and no significant values for LGA NB (p > 0.01). Secondary prophylactic outcomes presented decreased odds ratio for preeclampsia (OR = 0.17, 95% CI: 0.10-0.41). Conclusion: The use of metformin reduced cesarean section rates, resulted in a small number of patients to be treated, but it did not reduce LGA NB. Administering a lower dosage of metformin from the early stages to the end of treatment may yield significant results with fewer side effects.