Induction motors play a key role in the industrial sector. Thus, the correct diagnosis and classification of faults on these machines are important, even in the initial stages of evolution. Such analysis allows for increased productivity, avoids unexpected process interruptions, and prevents damage to machines. Usually, fault diagnosis is carried out by analyzing the characteristic effects caused by the faults. Thus, it is necessary to know and understand the behavior during the operation of the faulty machine. In general, monitoring these characteristics is complex, as it is necessary to acquire signals from the same motor with and without failures for comparison purposes. Whether in an industrial environment or in laboratories, the experimental characterization of failures can become unfeasible for several reasons. Thus, computer simulation of faulty motors digital twins can be an important alternative for failure analysis, especially in large motors. From this perspective, this paper presents and discusses several limitations found in the technical literature that can be minimized with the implementation of digital twins. In addition, a 3D finite element model of an induction motor with broken rotor bars is demonstrated, and motor current signature analysis is used to verify the fault effects. Results are analyzed in the time and frequency domain. Additionally, an artificial neural network of the multilayer perceptron type is used to classify the failure of broken bars in the 3D model rotor.

A number of lipophilic N-acyl-diamines and aldonamides have been synthesized and tested for their in vitro antiproliferative activity against Leishmania amazonensis and L. chagasi. Ribonamides, having one amino group, displayed good to moderate inhibition of parasite growth. The best result was obtained for compounds 10 and 15 with IC50 against L. chagasi below 5 μM.

Stifftia chrysantha J.C. Mikan é uma planta pertencente à família Asteraceae cujo principal uso pela população é o ornamental e atualmente se encontra sob risco moderado de extinção. É sabido que a planta foi utilizada no tratamento de afecções respiratórias por quilombolas. O objetivo deste estudo foi investigar o potencial efeito antimicrobiano de diferentes extratos de S. chrysantha contra algumas espécies de micobactérias e formas promastigotas de duas espécies de Leishmania. Os testes foram realizados in vitro utilizando MTT ou Resazurina em métodos colorimétricos, de acordo com o microrganismo avaliado. Os resultados mostraram baixa atividade dos extratos contra as culturas de micobactérias. Por outro lado, um efeito inibidor do crescimento foi observado no extrato metanólico das folhas e no extrato hexânico da casca contra as culturas de promastigotas de L. amazonensis (CI50 = 55,16 mg/mL extrato metanólico and 38,61 mg/mL extrato hexânico) and L. chagasi (CI50 = 72,05 mg/mL extrato hexânico). Novos estudos são necessários para descobrir as substâncias responsáveis pela inibição do crescimento das formas promastigotas.