AbstrakStaphylococcus aureus merupakan bakteri patogen penyebab infeksi oral, seperti: gingivitis, abses dentoalveolar, periodontitis, infeksi endodontik, bahkan karies gigi. Buah naga merah (Hylocereus polyrhizus) dan bit merah (Beta vulgaris L.) memiliki potensi menghambat S. aureus. Tujuan riset ialah membuktikan kandungan fitokimia ekstrak kulit naga merah dan bit merah secara kualitatif serta mengevaluasi perbandingan uji daya hambat dari kedua ekstrak tersebut terhadap S. aureus. Desain riset berupa eksperimental laboratoris dengan Rancangan Acak Lengkap faktorial. Tes antibakteri dilakukan dengan metode difusi sumuran. Bahan penelitian yang digunakan berupa ekstrak kulit naga merah dan bit merah 25%, 50%, 75% dan 100%. Data diolah dengan program SPSS 25.0. Analisis distribusi data yang normal memakai tes Shapiro-Wilk dan diteruskan memakai tes homogenitas ANOVA dua arah dan uji T-test untuk menguji signifikansi perbandingan kedua ekstrak. Hasil skrining fitokimia ekstrak kulit naga merah memperlihatkan keberadaan flavonoid, alkaloid dalam jumlah besar. Sedangkan ekstrak kulit bit merah menunjukkan komponen fenolik dan terpenoid berlimpah. Hasil penelitian menunjukkan adanya efektivitas antibakteri ekstrak kulit naga merah dan bit merah terhadap bakteri S. aureus. Efektivitas antibakteri kedua ekstrak bertambah seiring dengan pertambahan konsentrasi dari 25% sampai 100%. Analisa statistik data menunjukkan perbedaan signifikan antara kedua ekstrak, dimana ekstrak kulit buah naga merah ampuh menghambat S. aureus dibanding kulit bit merah.Kata Kunci : Antibakteri, Staphylococcus aureus, Hylocereus polyrhizus, Beta vulgaris L.
Red ginger extract has a category strong antibacterial effect on Staphylococcusaureus and Streptococcus mutans. Red ginger essential oil has the potential forstronger inhibition. This study aims to compare the antibacterial effectiveness of redginger essential oil against Staphylococcus aureus and Streptococcus mutans. Thedesign of this study was a laboratory experimental design with a factorial completelyrandomized design. The red ginger used in this study was proven to be a species ofZingiber officinale Roscoe. The production of essential oils in this study uses thesteam distillation method. The content of secondary metabolites in red ginger wastested quantitatively by the GC-MS method. Determination of antibacterial activityusing the disc diffusion method. The data were processed using the SPSS 21.0program. The normality of data distribution was tested with the Shapiro-Wilk test,followed by one-way ANOVA, Levene's test, and the Tukey HSD Post Hoc Test. Theresults of the antibacterial test of red ginger essential oil against Staphylococcusaureus (21.21mm ± 0.315) and Streptoococcus mutans (23.43mm ± 0.189) provedthat the inhibition power of the category was very strong at a concentration of 75%.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.