The copolymerization equation considering the penultimate unit effect, the so called penultimate model, takes a simplified shape in the case of rz = 0 (monomer 2, M,, does not homopolymerize). For this case a method analogous to the conventional KT(Ke1en-Tiid&transformation for estimation of r , and rl' is proposed. The new method was verified by literature data for the system styrene/fumarodinitrile, polymerized with benzoyl peroxide at 70"C, yielding rl = 0,062 and r,' = 0,812. Classification of copolymerization curves by means of the classical copolymerization model permits to distinguish between three curve-types: rl < 2 (alternation with respect to M3, rl = 2 (linear diagram with slope 0,5) and rl > 2 (non alternating system). The penultimate model permits to generate further curve-types of ''S'khape with r, < 2 and r,' > 2 or rl > 2 and r,' < 2 (rl = rl' for classically behaving systems and r, =k rl' for non-classically behaving systems).

Petri nets, also known as vector addition systems, are a long established model of concurrency with extensive applications in modeling and analysis of hardware, software, and database systems, as well as chemical, biological, and business processes. The central algorithmic problem for Petri nets is reachability: whether from the given initial configuration there exists a sequence of valid execution steps that reaches the given final configuration. The complexity of the problem has remained unsettled since the 1960s, and it is one of the most prominent open questions in the theory of verification. Decidability was proved by Mayr in his seminal STOC 1981 work, and, currently, the best published upper bound is non-primitive recursive Ackermannian of Leroux and Schmitz from Symposium on Logic in Computer Science 2019. We establish a non-elementary lower bound, i.e., that the reachability problem needs a tower of exponentials of time and space. Until this work, the best lower bound has been exponential space, due to Lipton in 1976. The new lower bound is a major breakthrough for several reasons. Firstly, it shows that the reachability problem is much harder than the coverability (i.e., state reachability) problem, which is also ubiquitous but has been known to be complete for exponential space since the late 1970s. Secondly, it implies that a plethora of problems from formal languages, logic, concurrent systems, process calculi, and other areas, which are known to admit reductions from the Petri nets reachability problem, are also not elementary. Thirdly, it makes obsolete the current best lower bounds for the reachability problems for two key extensions of Petri nets: with branching and with a pushdown stack. We develop a construction that uses arbitrarily large pairs of values with ratio R to provide zero testable counters that are bounded by  R . At the heart of our proof is then a novel gadget, the so-called factorial amplifier that, assuming availability of counters that are zero testable and bounded by  k , guarantees to produce arbitrarily large pairs of values whose ratio is exactly the factorial of  k . Repeatedly composing the factorial amplifier with itself by means of the former construction enables us to compute, in linear time, Petri nets that simulate Minsky machines whose counters are bounded by a tower of exponentials, which yields the non-elementary lower bound. By refining this scheme further, we, in fact, already establish hardness for h -exponential space for Petri nets with h + 13 counters.

When can two regular word languages K and L be separated by a simple language? We investigate this question and consider separation by piecewiseand suffix-testable languages and variants thereof. We give characterizations of when two languages can be separated and present an overview of when these problems can be decided in polynomial time if K and L are given by nondeterministic automata.

Several distinct techniques have been proposed to design quasi-polynomial algorithms for solving parity games since the breakthrough result of Calude, Jain, Khoussainov, Li, and Stephan (2017): play summaries, progress measures and register games. We argue that all those techniques can be viewed as instances of the separation approach to solving parity games, a key technical component of which is constructing (explicitly or implicitly) an automaton that separates languages of words encoding plays that are (decisively) won by either of the two players. Our main technical result is a quasi-polynomial lower bound on the size of such separating automata that nearly matches the current best upper bounds. This forms a barrier that all existing approaches must overcome in the ongoing quest for a polynomial-time algorithm for solving parity games.The key and fundamental concept that we introduce and study is a universal ordered tree. The technical highlights are a quasi-polynomial lower bound on the size of universal ordered trees and a proof that every separating safety automaton has a universal tree hidden in its state space.

Petri nets, also known as vector addition systems, are a long established model of concurrency with extensive applications in modelling and analysis of hardware, software and database systems, as well as chemical, biological and business processes. The central algorithmic problem for Petri nets is reachability: whether from the given initial configuration there exists a sequence of valid execution steps that reaches the given final configuration. The complexity of the problem has remained unsettled since the 1960s, and it is one of the most prominent open questions in the theory of verification. Decidability was proved by Mayr in his seminal STOC 1981 work, and the currently best published upper bound is non-primitive recursive Ackermannian of Leroux and Schmitz from LICS 2019. We establish a non-elementary lower bound, i.e. that the reachability problem needs a tower of exponentials of time and space. Until this work, the best lower bound has been exponential space, due to Lipton in 1976. The new lower bound is a major breakthrough for several reasons. Firstly, it shows that the reachability problem is much harder than the coverability (i.e., state reachability) problem, which is also ubiquitous but has been known to be complete for exponential space since the late 1970s. Secondly, it implies that a plethora of problems from formal languages, logic, concurrent systems, process calculi and other areas, that are known to admit reductions from the Petri nets reachability problem, are also not elementary. Thirdly, it makes obsolete the currently best lower bounds for the reachability problems for two key extensions of Petri nets: with branching and with a pushdown stack.At the heart of our proof is a novel gadget so called the factorial amplifier that, assuming availability of counters that are zero testable and bounded by k, guarantees to produce arbitrarily large pairs of values whose ratio is exactly the factorial of k. We also develop a novel construction that uses arbitrarily large pairs of values with ratio R to provide zero testable counters that are bounded by R. Repeatedly composing the factorial amplifier with itself by means of the construction then enables us to compute in linear time Petri nets that simulate Minsky machines whose counters are bounded by a tower of exponentials, which yields the non-elementary lower bound. By refining this scheme further, we in fact establish hardness for h-exponential space already for Petri nets with h + 13 counters. *