Abstract:The importance of lipids in the understanding of disease states is constantly increasing. Whilst the link between metabolic disorders and lipids seems to be clear, interpreting lipid regulation in the context of neuropsychiatric disorders is a new approach. Mental disorders account for almost 15% of the total global disease burden with Alzheimer's disease, depression or schizophrenia being amongst the most widespread mental disorders in the general population. For this reason rapid and early diagnosis is crucial and finding the right biomarkers is of great importance. Lipids appear to be essential in learning the aetiopathology of neuropsychiatric diseases as well as in biomarker research as they are most abundantly present in the brain. This study discusses recent findings in neuropsychiatry in the context of lipid analysis.

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Social, family and professional life depending on diverse factors. The caregiver burden is mainly related to patients with behavioral disturbances (BPSD) and loss of cognitive functions. Caring for a patient with dementia directly links to significant psychological stress. it also affects the caregivers' physical and mental health. The psychiatric morbidity is higher among the caregivers population. Depression, anxiety disorder and insomnia have been found to be the most common. in this article, the authors share their own experiences and reflections from the use of psychotherapy with caregivers. The primary goal of psychotherapy is to help the patient's caregiver adapt to the new situation and in improving relationships and communication with the patient. An important element of therapy is to reign in emotions associated with exercising care, helping with getting over the loss a loved one, accepting restrictions imposed on social and family life, and preventing feelings of loneliness. The aims of therapeutic interventions should include: education about dementia, improving the effectiveness and skills needed to deal with patients, and fostering a sense of security. it seems that the best kind of help for caregivers of people suffering from dementia, are their support groups.Autorzy dzielą się w artykule swoim doświadczeniem psychoterapeutycznym w zakresie pomocy osobom, które opiekują się członkami rodziny z postępującym otępieniem. Przedstawiają charakter różnych form pomocy, cele interwencji oraz sposoby rozwiązywania dylematów, przed którymi stają opiekunowie chorych oraz ich terapeuci.

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IntroductionMajor depressive disorder (MDD) in the older adults is correlated with a significant decline in daily physical activity, consequently resulting in chronically impaired quality of life and an increased exposure to falls-risk.ObjectivesEstablishing whether geriatric depression Scale (GDS) scores, found correlated with dual motor tasks (TUGTMAN), are also correlated under the cognitive test constraints (TUGCOG).AimsThe study aimed to analyse the relationship of MDD symptoms, the number of depressive episodes and hospitalisations, with the efficiency of gait in single and dual task conditions, motor and cognitive, functional capabilities.MethodsThe study was conducted in the outpatient clinic, university hospital, department of psychiatry, Krakow, on 30 patients over 60 years of age presenting recurrent MDD. The assessment consisted of GDS, MMSE, TUGT, TUGMAN, TUGCOG, 30sChS, SLS. Spearman rho rank correlation was applied to determine the relationship between the variables.ResultsStatistical analysis showed a significant association between the intensity of depressive symptoms expressed in the GDS and the number of completed episodes and depression and TUGT. The number of hospitalisations was associated with gait under motor (TUGMAN) and cognitive (TUGCOG) constraints.ConclusionDuration of the disorder and the number of hospital admissions are related to the functional efficiency of the single and dual-task performance in the persons suffering from this disorder for at least 10 years. Aged persons should effectively be encouraged to undertake physical activities.Disclosure of interestThe authors have not supplied their declaration of competing interest.