Molecular imprinted polymer is an artificial receptor made by imprinting molecules of a template in a polymer matrix followed by removing the template molecules via thorough washing to give the permanent template grooves. They show favored affinity to the template molecule compared to other molecules, and this property is the basic driving force for such diverse application of this techniques. Such techniques have been increasingly employed in a wide scope of applications such as chromatography, sample pretreatment, purification, catalysts, sensors, and drug delivery, etc., mostly in bioanalytical areas. A major part of them is related to development of new stationary phases and their application in chromatography and sample pretreatment. Embodiments of molecular imprinted polymer materials have been carried out in a variety of forms such as irregularly ground particles, regular spherical particles, nanoparticles, monoliths in a stainless steel or capillary column, open tubular layers in capillaries, surface attached thin layers, membranes, and composites, etc. There have been numerous review articles on molecular imprinted polymer issues. In this special review, the reviews in recent ca. 10 years will be categorized into several subgroups according to specified topics in separation science, and each review in each subgroup will be introduced in the order of date with brief summaries and comments on new developments and different scopes of prospects. Brief summaries of each categories and conclusive future perspectives are also given.

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The Kamlet-Taft * values of mixtures of water with four organic solvents over the entire range of composition have been estimated by solvatochromlc measurements with a series of carefully selected Indicators. The measured tr* value of each Indicator is colHnear with the average * value. We Interpret these results as indicating that the Indicators sense the polarlzabHIty/dlpolarlty and not the hydrogen bond acidity of the solvent. Examination of relationships between * and < and between £T and ir* and excess properties of *, ET, and e with respect to volume fraction of the organic cosolvent leads to the conclusion that the principal effect of changing the solvent composition on the observed * values operates through the dielectric properties of the local medium about the solute. This also supports the previous observation that solvatochromlc shifts of the Indicators used In this study are not very sensitive to solvent hydrogen bond acidity. The measured ir* values together with literature ET values were used to estimate a values, the hydrogen bond acidity parameter, of aqueous organic solvents.

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