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Paraneoplastic neurological syndromes occur because of immune-mediated neuronal dysfunction secondary to systemic malignancy, and the symptoms usually occur before the malignancy is discovered. Anti-Yo antibody is known to be an onconeural antibody that causes paraneoplastic cerebellar degeneration with ataxia

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Brainstem encephalitis is a rare, severe, and potentially life-threatening inflammation of the central nervous system that exhibits various treatment responses and outcomes owing to multiple etiologies [1]. However, owing to the risk of surgical biopsy of vulnerable structures such as the brainstem, the etiological evaluation of neuroinflammatory and immune-mediated brainstem lesions