Since traditional automation relies on wires, the machines’ versatility will be restricted. Thus maintenance is required to prevent cable wear and breakage, which would be costly and highlighted the importance of wireless connectivity in overcoming some of the limitations of conventional factory automation. Moreover, two of the most critical considerations, reliability and latency, need to be fulfilled so that a factory automation system can perform flawlessly. However, in factory automation, 0ms is the perfect condition since many machines share the same network. Furthermore, it can only reduce latency to a certain extent but not to zero. This study focuses on wireless networks for Industrial Automation Factor Automation’s system architecture, including network devices and topology, and then demonstrates one of the wireless networks’ main technologies, retransmission. This paper develops a mathematical analysis based on Negative Acknowledgement (NACK)-based retransmission mode as default retransmission for field devices to send data frames to the gateway device periodically. The results demonstrate an automatic on-demand retransmission (AODR) scheme able to provide higher efficiency of retransmission rate.