RESULTS: At baseline, there were no significant differences among groups for DI o [median values ranged from 1.97 (3.00) mM -1 for LM to 2.48 (3.14) mM -1 for HV]. After 6 months of exercise training, only the CL group significantly improved DI o [0.71 (0.28-1.15) mM -1 ;p=0.002]. Within-group changes for the exercise-only groups were 0.10 (-0.68-0.87) mM -1 for LM; -0.19 (-0.73-0.34) mM -1 for HM; and -0.41 (-0.83-0.02) mM -1 for HV. The Kruskal-Wallis test revealed changes in DI o were significantly better for the CL group compared to both high amount groups. CONCLUSIONS: For adults with prediabetes, combining a dietary intervention and weight loss with aerobic exercise improves DI o . Compared to findings from previous STRRIDE studies, improving β-cell function appears to be more challenging with aerobic exercise alone for those with a glycemic status closer to type 2 diabetes. Supported by NIH R01DK081559 828 Rate Of Torque Development Improvements Are Greatest Within First 2 Weeks Of Power-based Training