The development of androgenetic alopecia is associated with a risk of developing cardiovascular diseases, but the association of alopecia areata with cardiovascular diseases in humans is largely unexplored. We measured the plasma level of two common cardiovascular disease markers, cardiac troponin I and C-reactive protein, in alopecia areata and androgenetic alopecia affected subjects. Also, we investigated the possible presence of pro-apoptotic factors in the plasma of hair loss subjects. The mean plasma cardiac troponin I level was highest in alopecia areata subjects, moderately higher in androgenetic alopecia subjects, and lowest in subjects without hair loss (p <0.05). Alopecia areata subjects not receiving treatments had highest levels of cTnI (p <0.05). Alopecia areata plasma samples with high cardiac troponin I levels also induced significantly higher rates of cardiomyocyte apoptosis in cell culture assays. The results suggest the potential for increased heart remodelling. Close monitoring of cardiovascular health in alopecia areata subjects, as well as subsets of androgenetic alopecia patients, may be appropriate.
As a new type of pulsed power supply, air-core pulsed alternators concentrate all the functions of energy storage, energy conversion and power conditioning in one machine. It is also easy to condition the output voltage and current waveforms. These advantages make it a promising compact power supply system for a variety of fields including laser and electromagnetic launchers. The whole work process of a two-phase air-core pulsed alternator can be divided into self-excitation process, discharge process and energy reclaim process. The aim of the self-excitation is to generate an adequate current in the exciting winding for the discharge process and there is a condition to realize a successful self-excitation for a two-phase air-core pulsed alternator. In this paper, the relationship between the successful self-excitation condition and the design parameters of the aircore pulsed alternator was established. A comparison of the successful self-excitation condition between a single-phase aircore pulsed alternator and a two-phase alternator was also made. To verify the conclusions of the paper, some simulations were performed on a single-phase air-core pulsed alternator and a two-phase air-core pulsed alternator. Each phase armature winding of the two-phase alternator shares the same electrical parameters as the single-phase alternator. The results and conclusions of the analyses and simulations in this paper can offer guidance for the flexible design and optimization of twophase air-core pulsed alternators.
As an important force part of the Bridge, the precise positioning of the construction of anchorage system is especially important. Combining with the practice of bridge engineering, this paper introduces the precise positioning of anchorage system by two-point reference line lofting principle. The results have proved that all the deviations satisfy the requirements of regulation by reference line lofting. This method decreases the cost, increases the measuring accuracy. It is worth wide spreading.
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