Objective. To explore the prenatal ultrasonographic characteristics and pregnancy outcomes of fetal meconium peritonitis (FMP). Methods. Nine patients diagnosed with FMP by routine prenatal examination between January 2015 and December 2020 were identified. Both prenatal ultrasonographic characteristics and pregnancy outcomes associated with these patients were retrospectively analyzed. Results. The mean gestational age at the time of FMP diagnosis was 31.3 ± 4.8 weeks, and the mean gestational age of delivery was 35.1 ± 5.1 weeks. Prenatal ultrasonographic findings at the time of diagnosis in these patients included intestinal dilatation (9/9, 100%), intraperitoneal calcification (8/9, 88.9%), fetal ascites (5/9, 55.6%), intraperitoneal pseudocyst (5/9, 55.6%), and polyhydramnios (6/9, 66.7%). Analyses of the etiological basis for meconium peritonitis in 5 of the 8 live births that underwent surgical treatment revealed 4 cases of congenital volvulus and 1 case of jejunal atresia. Conclusion. The prenatal ultrasound manifestations of fetal meconium peritonitis are diverse, and the different grades of prenatal ultrasound manifestations can provide important information for the treatment of perinatal infants.

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Background: Sleep quality and exercise frequency are closely associated with coronary heart disease (CHD). Few studies focused on the joint effect of initiating sleep, sleep disorders and exercise frequency on the risk of CHD in elderly. Based on Boshan Elderly Cohort Study (BSECS), we explored the sleep quality, exercise frequency and their joint effects on the risk of CHD.Methods: We collected 678 participants whose age ≥60 years old from Boshan district hospital. We used Pittsburgh Sleep Quality Index (PSQI) to evaluate the sleep quality, and obtained physical examination information from hospital.Results: Compared with non-CHD group, CHD patients spent more time in initiating sleep (time≥60mins, 34.59% vs 22.93%, P=0.025), and less time in exercising(exercise frequency<1times/week, 23.90% vs 17.15%, P=0.024). In multiple logistic regression analysis, sleep latency ≥ 60 mins were associated with CHD risk (adjusted OR=1.82; 95%CI: 1.16, 2.86; P=0.010). The adjusted OR (95%CI) of CHD was 2.24 (1.16, 4.34) for sleep duration <5 hours vs 5 - 9 hours. Compared with exercise frequency <1 times/week, the adjusted OR for exercise frequency ≥ 1 times/week was 0.66 (95% CI: 0.44, 0.98; P=0.037). In addition, the joint effects of long sleep latency (≥ 60 mins) and sleep disorders were associated with CHD (adjusted OR=3.29; 95%CI: 1.35,7.98; P=0.009), and the joint effect of exercise frequency ≥ 1 times/week and good initiating sleep were also associated with CHD, the adjusted OR (95%CI) was 0.39 (0.20, 0.77).Conclusions: Long sleep latency, high frequency of initiating sleep difficulty, sleep disorders and short sleep duration were positively associated with CHD. In addition, the joint effect of long sleep latency and sleep disorders were positively correlated with CHD incident, however, the joint effect of exercise frequency ≥ 1times/week and good initiating sleep were negatively associated with the risk of CHD.