Omniphobic
and slippery coatings from lubricant-infused, textured
surfaces have recently been shown to have superior properties including
low contact angle hysteresis and low sliding angles. Here, we present
an omniphobic slippery surface prepared by infusing a fluorinated
lubricant into a porous polyelectrolyte multilayer. These surfaces
repel water and decane with sliding angles as low as 3°. One
advantage of polyelectrolyte multilayers is the ease with which they
can coat nonplanar surfaces, demonstrated here.
Layer-by-layer assembly of films containing metal ions was investigated. A complex between various metal ions and branched polyethyleneimine is formed in solution and then assembled into multilayer films with poly(acrylic acid). The metal-ligand complex formation results in brightly colored materials that deposit as thick layers. Cu(2+)-containing films were chosen as a model for studying the disassembly of these films in response to various stimuli, including pH, salt, and surfactants. The range of pH instability corresponds to the pH range over which pores are formed in the film. We demonstrate controllable disassembly of these materials, which could be used for antifungal or antibacterial applications.
Facile dip-coating method to fabricate robust polypyrrole thin film coating on thermal insulation polypropylene membrane with solar vapor generation efficiency of 72%.
Objectives
Alveolar bone osteoporosis has attracted more and more attention because of its profound impact on stomatognathic function and treatment, but current treatments have not been targeted to alveolar bone and might even cause severe side effects. Thus, identifying the effects of anti‐osteoporosis agents on alveolar bone is essential. Icariin ameliorates metabolic dysfunction of long bones, but its effects on alveolar bone remain unclarified.
Materials and methods
BMSCs were isolated from rat mandibles (mBMSCs). The osteogenic potential of mBMSCs and the signalling pathway involved under icariin treatment were measured by ALP and alizarin red staining, reverse transcription‐polymerase chain reaction (RT‐PCR), Western blotting and immunofluorescence. Dual‐luciferase assay, chromatin immunoprecipitation (ChIP) and co‐immunoprecipitation were used to investigate the molecular mechanism. Ovariectomized and sham‐operated rats treated with or without icariin were analysed by micro‐CT, TRAP staining and calcein double labelling.
Results
We found that icariin promoted osteoblast differentiation of mBMSCs. Furthermore, STAT3 was critical for icariin‐promoted osteoblast differentiation, as indicated by increased phosphorylation levels in icariin‐treated mBMSCs, while preventing STAT3 activation blocked icariin‐induced osteoblast differentiation. Mechanistically, icariin‐promoted transcription of the downstream osteogenic gene osteocalcin (Ocn) through STAT3 and STAT3 bound to the promoter of Ocn. Notably, icariin prevented the alveolar bone osteoporosis induced by oestrogen deficiency through promoting bone formation.
Conclusions
For the first time, our work provides evidence supporting the potential application of icariin in promoting osteogenesis and treating alveolar bone osteoporosis.
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