In this research, by simultaneously regulating the two major factors affecting the plasmonic enhanced fluorescence (PEF), spectral overlap and the distance between the fluororophores and the noble metal nanoparticles, a significantly enhanced fluorescent signal is achieved. Core‐shell nanostructures composed of aspect ratio (AR) adjustable gold nanorods (GNRs) and various thickness of SiO2 are prepared and the decorated fluorophores are realized optimized PEF. A typical stimuli‐responsive conjugated polymer, polydiacetylene (PDA), and a near‐infrared (NIR) dye Cy5.5 are selected as fluorophores and their fluorescent signal are enhanced 7.26 and 4.41 times, respectively. Based on the optimized optical properties, a multifunctional antibody modified Mab‐Cy5.5‐GNRs@SiO2 is successfully demonstrated the targeting, imaging, and photothermal therapy (PTT) effects on SKOV‐3 ovarian cancer cells.

In this study, we prepared novel hybrid assemblies composed of a Schiff base small molecule, (E)-1-(4-(dimethylamino)-phenyl)iminomethyl-2-hydroxyl-naphthalene (DPIN) and single strand DNAs (ssDNAs). Owing to clustering-triggered emission (CTE), aggregated hybrid assemblies...

The significance of DNA is no longer limited to its role as a biological information carrier; as a natural polymer, it also become in the field of materials. Single-stranded DNA (ssDNA) molecules with specific sequences can form a G-quadruplex or hairpin-shaped conformation with specific heavy metal ions through coordination bonds. In this study, ssDNA molecules of the four sequences were prepared into hybrid assemblies with one of the famous display materials, the tris-(8-hydroxyquinoline)aluminum (Alq3) semiconductor. Based on these hybrid assemblies, heavy metal ions, namely Pb2+, Hg2+, Cd2+ and As3+, were detected individually at the ppb level. Apart from this, in practical application, many samples containing heavy metal ions are digested with acid. By introducing MES buffer solution, the influence of acidity on the fluorescent signal of Alq3 was excluded. This strategy showed promising results in the practical application of detecting heavy metal ions in shrub branches and leaves.