Ischaemic reperfusion (IR) injury is characterized as the damage caused to the tissues due to the return of blood supply (reperfusion) after a brief duration of lack of oxygen (ischaemia). Affecting a wide range of population and organs, they are usually observed as a consequence to conditions such as trauma, shock, strangulation, mesenteric artery thrombosis and intestinal obstruction. 1-4 Ischaemia by itself damages the cells, which is further exacerbated by the restoration of blood flow resulting in increased cell death and release of inflammatory response elements that ultimately leads to multiple organ failure. 5 Of the organs affected by IR injury, the intestine has been described as the most vulnerable to this damage and severe intestinal injury could lead to the need for immediate surgical
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.