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Adjunctive exenatide treatment for > or = 3 years in T2DM patients resulted in sustained improvements in glycemic control, cardiovascular risk factors, and hepatic biomarkers, coupled with progressive weight reduction.

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Abstract. This study examined surface air temperature trends over global land from 1901-2009. It is found that the warming trend was particularly enhanced, in the boreal cold season (November to March) over semi-arid regions (with precipitation of 200-600 mm yr −1 ) showing a temperature increase of 1.53 • C as compared to the global annual mean temperature increase of 1.13 • C over land. In mid-latitude semi-arid areas of Europe, Asia, and North America, temperatures in the cold season increased by 1.41, 2.42, and 1.5 • C, respectively. The semi-arid regions contribute 44.46 % to global annual-mean land-surface temperature trend. The mid-latitude semi-arid regions in the Northern Hemisphere contribute by 27.0 % of the total, with the midlatitude semi-arid areas in Europe, Asia, and North America accounting for 6.29 %, 13.81 %, and 6.85 %, respectively. Such enhanced semi-arid warming (ESAW) imply drier and warmer trend of these regions.