Background Primary duodenal cancer (PDC) is rare, especially signet-ring cell carcinoma (SRCC) of the duodenal bulb, and it is commonly misdiagnosed as an ulceration. Here, we report a rare case of SRCC of the duodenal bulb presenting with gastrointestinal hemorrhage in an 82-year-old man. Case presentation An 82-year-old man was admitted for gastrointestinal hemorrhage. Physical examination revealed upper abdominal tenderness and pale appearance, but was otherwise unrevealing. Laboratory workup was significant for anemia. Imaging showed no abnormalities. Two endoscopic evaluations along with interventional embolization were attempted and, unfortunately, adequate hemostasis was not achieved, resulting in distal subtotal gastrectomy, including the duodenal bulb. SRCC of the duodenal bulb was diagnosed based on pathology after surgery. Post-operatively, the patient experienced persistent gastrointestinal bleeding. Family declined further intervention and the patient eventually died one month post-resection. Conclusions SRCC in the duodenal bulb is difficult to diagnose. For those with high-risk factors, endoscopic examination and biopsy are recommended. For patients who can receive radical tumor resection, pancreaticoduodenectomy (PD) is considered a first-line option. Early diagnosis and resection have been shown to improve prognosis.

Abstract. To evaluate the user experience in the human-computer interaction design of intelligent products, the quality of color design is a key factor. The purpose of this article is to design the human-computer interaction in smart phones through the study of color semantics, which is one of the branches of product semantics. In particular, the application of color semantics in UI design would help designers better meet user's needs and improve user's experience in the human-computer interaction design of smart products.

Through the analysis of the development and status quo of cultural creative product design and the analysis of the characteristics of national cultural concepts, the author tries to propose the key points of the national cultural creative product design method from the perspective of internationalization. Using the literature research method, it sorts out the development and current situation of the design concept of cultural and creative products; it also carries out functional classification of cultural and creative products; and it discriminates the concept of national culture; Finally, through the summary of the existing research directions and contents of the combination of national culture and creative product design, it is proposed that from the perspective of internationalization, designers can only accurately convey the image of national culture to users through creative products if they have a deep understanding of all aspects of national culture. Through the grasp of three aspects of emotion, inheritance and interactivity, it can help designers to effectively carry out innovative design of national cultural products from the perspective of internationalization.

While research about contemporary Asian arts exhibited in mega museums has attracted growing attention, there is little dialogue concerning community-based art practices in everyday Asian and Asian American neighborhoods. This interview article highlights community-based art projects led by a grassroots organization, the Chinese Culture Center of San Francisco (CCC), to help understand Chinatown’s stories as shared and lived by the community during a challenging time. Hoi Leung, CCC’s chief curator, explained how the organization mobilized art to share diverse local stories, celebrate a sense of belonging, and raise public awareness about racial justice issues within the communities it serves. To counter socially constructed assumptions about Chinatown and its residents, CCC actively develops cross-sector partnerships to centralize underrepresented voices through community-based arts and projects.