Recent work in domain adaptation bridges different domains by adversarially learning a domain-invariant representation that cannot be distinguished by a domain discriminator. Existing methods of adversarial domain adaptation mainly align the global images across the source and target domains. However, it is obvious that not all regions of an image are transferable, while forcefully aligning the untransferable regions may lead to negative transfer. Furthermore, some of the images are significantly dissimilar across domains, resulting in weak image-level transferability. To this end, we present Transferable Attention for Domain Adaptation (TADA), focusing our adaptation model on transferable regions or images. We implement two types of complementary transferable attention: transferable local attention generated by multiple region-level domain discriminators to highlight transferable regions, and transferable global attention generated by single image-level domain discriminator to highlight transferable images. Extensive experiments validate that our proposed models exceed state of the art results on standard domain adaptation datasets.

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The present meta-analysis indicated that preoperative NLR had significant association with the prognosis of hepatocellular carcinoma patients and may be an effectively prognostic indicator.

Aim: To assess the clinical and laboratory features of primary Sjogren's syndrome (pSS) in a large teaching hospital in China.Methods: Three hundred and fifteen pSS patients diagnosed according to American-European Classification Criteria and consecutively admitted to Anhui Provincial Hospital from 1 January 1999 to 30 September 2012 were retrospectively selected in this study. Results:The median age was 46.8 AE 14.4 years (range 13-83 years) and the majority of patients were female (96.5%). The common clinical features at initial presentations were dry mouth (50.2%), dry eyes (31.4%) and joint pain (24.8%); 92.6% of patients had positive anti-SSA antibody and 49.2% patients had positive anti-SSB antibody. One hundred and eighteen patients underwent labial salivary gland biopsy. According to Chisholm grading criteria, grade 3 to 4 was present in 58.5% of the patients. The frequency of interstitial lung disease (ILD) occurred (20.9%) in the patients with systemic extraglandular manifestations. The patients with ILD were frequently associated with positive anti-SSA (P = 0.005) and low levels of C3. The most common impairment of lung function was small airway function abnormalities. Sixty-six pSS patients with ILD (pSS-ILD) were diagnosed with high-resolution computed tomography and treated with corticosteroids and/or immunosuppressants, in which 18 patients had improved pulmonary function.Conclusion: Labial salivary gland biopsy and anti-nuclear antibodies spectrum were important to the diagnosis of pSS. The pSS patients had high percentage of ILD, especially small airway function abnormalities. The combination of corticosteroids and immunosuppressants appears to be effective in treatment of pSS patients with ILD.

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