Infantile myofibromatosis (IM) is the most common fibrous tumor of infancy. IM may arise in a solitary or multicentric form, with similar histopathological findings, however, the clinical features and prognoses may vary. The solitary form tends to occur predominantly in males and is typically observed in the dermis, subcutis or deep soft tissues. The reported incidence of solitary osseous myofibromatosis is rare. Furthermore, the majority of solitary IM cases of the bone occur in the craniofacial bones, while the occurrence of solitary osseous myofibromatosis on the extremities has been sporadically reported. The present study describes two cases of solitary IM involving the bones of the upper extremities in females who were over two years old. The cases show unusual symptom presentation and the tumor origin is in a rarely observed location. The study discusses the clinical, radiological and pathological features, in addition to the previously described etiology, prognosis and treatment options for this condition.

The purpose of this article is to evaluate the clinical outcomes of a posterior chamber phakic intraocular lens (pIOL) (Visian Implantable Collamer Lens V4c) for the correction of moderate to high myopia in Chinese eyes.The article is designed as a retrospective case series.This study included the first consecutive eyes that had implantation of a new pIOL design with a central hole, at our department by the same surgeon. The safety, efficacy, predictability, stability, and adverse events of the surgery were evaluated over 6 months.The study enrolled 63 eyes (32 patients). The mean spherical equivalent decreased from −12.81 ± 3.11 diopters (D) preoperatively to −0.05 ± 0.27 D 6 months postoperatively; 96.8% of eyes were within ±0.50 D of the target and 100% of eyes were within ±1.00 D. All eyes had a decimal uncorrected distance visual acuity of 0.5 (20/40) or better at every follow-up visit. The safety and efficacy indices were 1.42 ± 0.34 and 1.11 ± 0.19, respectively. Postoperatively, the intraocular pressure (IOP) remained stable over time. No significant rises in IOP (including pupillary block) and no secondary cataract were found. After 6 months, the mean vault was 505.2 ± 258.9 μm (range 120–990 μm), and the mean endothelial cell loss was 2.0%.Implantation of the pIOL was safe, effective, predictable, and stable in the correction of moderate-to-high myopia in Han Chinese patients, even without peripheral iridectomy.

No author has a financial or proprietary interest in any material or method mentioned.

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The flexible piezoelectric energy harvester (FPEH), as an effective strategy for long-term power supply of implantable and wearable electronics, requires high areal output energy density, low mechanical stiffness, and high energy efficiency, simultaneously. The widely adopted sandwich FPEH, consisting of one relatively hard substrate sandwiched between two piezoelectric films, can provide a high areal output energy density, but also high mechanical stiffness and low energy efficiency due to its energy-wasting deformation of the hard substrate. Here, we propose a novel optimal soft-substrate sandwich FPEH with designs of sufficient length and optimized Young's modulus of the substrate, which is much smaller than that of the piezoelectric film. A sandwich beam model considering both the bending and shearing of the soft substrate and the one-way coupling of the piezoelectric effect was adopted for the theoretical analysis and optimal design. The optimal soft-substrate sandwich FPEH exhibits greatly improved overall performance with a 33% increase in areal output energy density, a 51% reduction in mechanical stiffness, and a 177% increase in energy efficiency, simultaneously. Systematic theoretical analysis is performed to illustrate the mechanism and guide the optimal design. The novel optimal soft-substrate sandwich FPEH is then applied to harvesting energy from various living subjects. This optimal design can be extended to other types of mechanical energy harvesters with a similar laminated structure.