Fourier-domain full-field optical coherence tomography (FD-FF-OCT) has the advantages of high resolution and parallel detection. However, using parallel detection can result in optical crosstalk. Toward minimizing crosstalk, we implemented a very fast deformable membrane (DM) that introduces random phase illumination, which can effectively reduce the crosstalk by washing out fringes originating from multiply scattered light. However, for one thing, although the application of DM has reduced the crosstalk problem in parallel detection to a certain extent, there will still be a lot of background noises, which may come from the circadian rhythm of the sample and multiple scattered photons. The problem could be solved by employing the adaptive singular value decomposition (SVD) filtering. We also combined SVD with the cumulative sum method, which can improve image resolution well. For the other thing, the random phase introduced by DM in the spectral domain will cause axial crosstalk after inverse Fourier transform. As far as we know, we are the first team to notice axial crosstalk and proposes that this problem can be solved by controlling the deformation range of DM. We have carried out a theoretical analysis of the above methods and verified its feasibility by simulation.

Full field optical coherence tomography (FF-OCT) has the advantage of ultrahigh lateral resolution (∼1 µm) resulting from a relatively high numerical aperture (NA) micro objective. However, usually the field of view of micro objective is limited. Furthermore, in vivo imaging, significant motion artifacts limit the performance of traditional FF-OCT where the quality of the restored image is generally degraded due to the influence of motion artifacts. In this paper, we propose a method of edge-preserving ptychography based on dual-balanced time domain FF-OCT, which we can call it time-domain ptychography full field optical coherence tomography (TD-POCT). The method combines the advantages of both ptychography and dual-balanced FF-OCT, which can overcome the limitation of the field for view of micro objective and suppresses motion blur. Moreover, this method can recover not only the amplitude of each layer, but also the phase information. So in addition to tomography, the system can also be used for surface 3D object reconstruction. Numerical simulation verifies that both the horizontal and vertical resolution can reach a few microns.