Background: It has been reported that the knowledge, attitudes and practices of nurses play a significant role in preventing incontinence-associated dermatitis (IAD), and these three factors influence and interact with each other. This study aimed to translate the English version of the Knowledge, Attitudes and Practices of Incontinence-Associated Dermatitis Questionnaire (KAP-IAD-Q) into Chinese and assess the validity and reliability of the Chinese KAP-IAD-Q (C-KAP-IAD-Q) used with Chinese nurses. Methods: The KAP-IAD-Q was translated into Chinese strictly in accordance with the Brislin translation model, and a Chinese version of IAD was formed after discussion by experts. From October to November 2021, a total of 259 Chinese nurses were recruited through a convenience sampling method and investigated using the Chinese version of the knowledge, attitudes and practices of the incontinenceassociated dermatitis questionnaire (C-KAP-IAD-Q) and the general self-efficacy scale to assess its reliability and validity.Results: Three factors were extracted by exploratory factor analysis comprised of 22 items. The Cronbach's α coefficients were 0.961, 0.929 and 0.833, and the intraclass correlation coefficient was 0.98 totally. The scale-level content validity index (S-CVI) was 0.95, and the item-level content validity (I-CVI) was 0.83-1.00. The correlation coefficient between the general self-efficacy scale and the C-KAP-IAD-Q was 0.561 (P < 0.01). Conclusion:The 22-item C-KAP-IAD-Q seems to be culturally well adapted and has good psychometric properties used by Chinese nurses.