In this paper, the solubility of methanesulfonamide (MSAM) in selected 13 pure solvents including 9 alcohols (methanol, ethanol, n-propanol, iso-propanol, n-butanol, sec-butanol, iso-butanol, n-pentanol, and iso-pentanol) and 4 esters (ethyl acetate, propyl acetate, iso-propyl acetate, and methyl propionate) at atmospheric pressure and temperatures from 283.15 to 323.15 K was determined. The solubility as a function of temperature was regressed using modified Apelblat, Van’t Hoff, λh, Wilson, and nonrandom two-liquid (NRTL) models. Based on the experimental and the simulation results, the thermodynamic mixing properties of the solutions, mixing Gibbs energy, enthalpy, and entropy were evaluated.

In this paper, the solubility of menadiol diacetate in nine alcohols (methanol, ethanol, n-propanol, i-propanol, nbutanol, i-butanol, n-amyl alcohol, i-amyl alcohol, and cyclohexanol) and five n-alkyl acetates (methyl acetate, ethyl acetate, n-propyl acetate, n-butyl acetate, and amyl acetate) was experimentally measured with the aid of a laser dynamic device at temperatures from 283.15 to 323.15 K. The solubility of menadiol diacetate as a function of temperature was regressed in terms of three semiempirical solubility models (Apelblat, van't Hoff, and λh), two activity coefficient solubility models (Wilson and NRTL), and the Jouyban model. The thermodynamic mixing properties (mixing Gibbs energy, entropy, and enthalpy) of the solutions were estimated in terms of the measured solubility data and the regressed parameters of the Wilson model.