Single-cell RNA sequencing (scRNA-seq) is emerging as a promising technology. There exist a huge number of genes in a scRNA-seq data. However, some genes are high quality genes, and some are noises and irrelevant genes because of unspecific technology reasons. These noises and irrelevant genes may have a strong influence on downstream data analyses, such as a cell classification, gene function analysis, and cancer biomarker detection. Therefore, it is very significant to obviate these irrelevant genes and choose high quality genes by gene selection methods. In this study, a novel gene selection and classification method is presented by combining the information gain ratio and the genetic algorithm with dynamic crossover (abbreviated as IGRDCGA). The information gain ratio (IGR) is employed to eliminate irrelevant genes roughly and obtain a preliminary gene subset, and then the genetic algorithm with a dynamic crossover (DCGA) is utilized to choose high quality genes finely from the preliminary gene subset. The main difference between the IGRDCGA and the existing methods is that the DCGA and IGR are integrated first and used to select genes from scRNA-seq data. We conduct the IGRDCGA and several competing methods on some real-world scRNA-seq datasets. The obtained results demonstrate that the IGRDCGA can choose high quality genes effectively and efficiently and outperforms the other several competing methods in terms of both the dimensionality reduction and the classification accuracy.

To implement co-operation among applications on the Internet of Things (IoT), we need to describe the meaning of diverse sensor data with the sensor ontology. However, there exists a heterogeneity issue among different sensor ontologies, which hampers their communications. Sensor ontology matching is a feasible solution to this problem, which is able to map the identical ontology entity pairs. This work investigates the sensor ontology meta-matching problem, which indirectly optimizes the sensor ontology alignment’s quality by tuning the weights to aggregate different ontology matchers. Due to the largescale entity and their complex semantic relationships, swarm intelligence (SI) based techniques are emerging as a popular approach to optimize the sensor ontology alignment. Inspired by the success of the flower pollination algorithm (FPA) in the IoT domain, this work further proposes a compact FPA (CFPA), which introduces the compact encoding mechanism to improve the algorithm’s efficiency, and on this basis, the compact exploration and exploitation operators are proposed, and an adaptive switching probability is presented to trade-off these two searching strategies. The experiment uses the ontology alignment evaluation initiative (OAEI)’s benchmark and the real sensor ontologies to test CFPA’s performance. The statistical comparisons show that CFPA significantly outperforms other state-of-the-art sensor ontology matching techniques.

Developing sensor ontologies and using them to annotate the sensor data is a feasible way to address the data heterogeneity issue on Internet of Things (IoT). However, the heterogeneity issue exists between different sensor ontologies hampers their communications. Sensor ontology matching aims at finding all the heterogeneous entities in two ontologies, which is a feasible solution for aggregating heterogeneous sensor ontologies. This work investigates swarm intelligence (SI)-based sensor ontology matching techniques and further proposes a competitive binary particle swarm optimization algorithm (CBPSO)-based sensor ontology matching technique. In particular, a guiding matrix (GM) is proposed to ensure the population’s diversity and a competitive evolutionary framework is presented. The experiment uses ontology alignment evaluation initiative (OAEI)’s benchmark and three real sensor ontologies to test CBPSO’s performance. The experimental results show that the competitive evolutionary framework is able to help CBPSO effectively optimize the alignment’s quality, and it significantly outperforms other SIs at 5% significant level.