Long-term monitoring for patients can improve patient safety, help doctors diagnose and evaluate the clinical situation. Limited manpower in hospitals makes it difficult to achieve continuous and nuanced monitoring. In this paper, we classify the patient's posture as standing, sitting, lying and falling. Using a non-intrusive, privacy-compliant lidar, a medical human pose dataset is collected in the First Affiliated Hospital, Sun Yat-Sen University, and a novel computer vision-based approach is presented to continuously detect patients pose and provide timely information to health care workers. The recognition accuracy reaches 93.46% and the recognition speed reaches 42FPS on 3080Ti. Experimental results show that the algorithm performs well on the medical human pose dataset, and can effectively solve the problem of human pose recognition in medical scenes.
The knowledge of accurate geometrical parameters from X-ray diffraction studies in the solid state of metal nucleotide is very important for understanding the relationship between structures and properties, including biochemical processes and even enzyme–metal–substrate interactions. The research is also very necessary to precisely and controllably design the functional materials. Here, seven types of coordination polymers of inosine 5′-diphosphate nucleotide (IDP) with transition metals, {[Zn(HIDP)(azpy)(H2O)2]·4H2O} n (1), {[Cd2(IDP)2(bpda)2]·[Cd(H2O)6]·11H2O} n (2), {[Cd3(IDP)2(4,4′-bipy)2(H2O)3]·6H2O} n (3), {[Cd2(IDP)2(bpe)2(H2O)2]·(H2bpe)·26H2O} n (4), {[Cu3(IDP)2(azpy)2(H2O)5]·5H2O} n (5), {[Cu3(IDP)2(bpe)2(H2O)5]·9H2O} n (6), and {[Co(HIDP)(azpy)(H2O)2]·7H2O} n (7) [4,4′-bipy = 4,4′-bipyridine, azpy = 4,4′-azopyridine, bpe = 1,2-bis(4-pyridyl)ethene, and bpda = 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene], were designed, synthesized, and firmly characterized using single-crystal X-ray diffraction. The coordination patterns of the diphosphate group of IDP in these complexes were studied by crystallographic analysis, namely, open, close, and open–close hybrid types. We have investigated the diverse coordination patterns of the diphosphate group and its spatial relationship relative to the pentose ring on the basis of two conformational parameters, the pseudorotation phase angle and the degree of puckering. Crystallographic studies clearly reveal the correlation between the backbone torsion angle (ω′ and φ) of the sugar–diphosphate and the conformational preference of the pentose ring, i.e., the signs of the backbone torsion angles ω′ and φ are both plus (+) or minus (−), the conformation of the pentose ring is envelope form (E), while when one of the two signs is plus (+) and the other is minus (−), the pentose ring is in the twist form (T). This is the first time elucidation of the coordination pattern of diphosphate relative to the conformation of the pentose ring in nucleotide metal complexes, which are different from the other inorganic or organic diphosphate compounds. The chirality of these coordination polymers was examined by combining solid-state circular dichroism spectroscopy measurements with the explanation of their crystal structures. The results presented in this paper are very important for understanding their nucleotide coordination chemistry, their supramolecular chemistry, and even their biochemistry.
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