This study aims to investigate the effects of different selenium (Se) sources on the growth performance of Chinese broilers and provide a scientific rationale for adding Se additives to broiler feed. Relevant studies that meet standard inclusion criteria were identified and extracted from China National Knowledge Infrastructure and Wanfang and Chinese Scientific Journal (VIP) databases. A total of 9 studies with 539 subjects were included. A meta-analysis was performed with STATA15.0 to estimate the combined standardized mean difference (SMD) with a 95% confidence interval (95% CI). Heterogeneity test of articles was examined by Q-test, and the results showed that P values of feed conversion ratio, average daily gain (ADG), and average daily intake were all less than 0.05, suggesting a strong heterogeneity among the selected literature. Therefore, the random effect model is selected to calculate the SMD of the three indexes. The combined SMDs (95% CI) of feed:gain, ADG, and average daily feed intake (ADFI) were −0.39 (−1.03, 0.25), 0.26 (−0.29, 0.81), and −1.45 (−3.09, 0.20), respectively, and the P values were all less than 0.05. This study shows that the absolute differences in the growth performance (feed:gain, ADG, and ADFI) of broilers fed with either organic or inorganic Se supplements at the same dose were quite small. The P values of Egger’s test were 0.770, 0.089, and 0.426, respectively, for the above indexes, showing no significant publication bias. Sensitivity analysis ensured the stability and reliability of the results. In summary, the effects of organic and inorganic Se in feed on the growth performance of broilers are statistically equal.
This study aims to evaluate the influence of rumen-protected methionine (RPM) on the milk yield and milk compositions of dairy cows by employing a meta-analysis method. The articles in the publication databases between January 2010 and January 2022 which reported on various concentrations of RPM supplements in dairy cow diets and then monitored the milk yield and milk compositions were searched. A total of 14 studies were included, covering 27 treatments with a total of 623 dairy cows. Comprehensive Meta-Analysis V3 was used for statistical analysis, the forest map was drawn by the standard mean difference (SMD) with a 95% confidence interval (95% CI), and the SMD was calculated by a random effect model. The dose effect curve was drawn by fitting the SMD and RPM dose of each study to explore the optimal dosage of RPM. Compared with the basal diet, the RPM supplement significantly increased the percentages of milk fat (SMD (95% CI): 1.017% [0.388, 1.646]) and milk protein (SMD (95% CI): 0.884 [0.392, 1.377]). However, the milk yield (SMD (95% CI): 0.227 kg/d [−0.193, 0.647]) and lactose concentration (SMD (95% CI): 0.240% [−0.540, 1.020]) were not affected. The subgroup analysis found that the effect of the RPM supplement on the milk fat and milk protein was greater in the high-protein feed than in the low-protein feed. Multiple regression analysis showed that feeding RPM significantly improved the milk yield and milk protein percentage of dairy cows. The results of the dose–effect analysis show that the optimal range for the RPM was 7.5–12.5 g/d. RPM supplements in a dairy diet can improve the milk protein percentages and milk fat percentages of dairy cows.
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