Recently, the concept of micro-ecological skin care has gradually been into people's life, which means that people have entered a new era in skin care. Micro-ecological skin care mainly refers to the improvement of skin barrier function and cell combination, accelerating of skin renewal and improvement of skin health by supplementing probiotics or prebiotics. 1 Probiotics are defined as living microorganisms which, when administered in adequate amounts, give a healthy benefit on the host. 2 Reports on the use of probiotics can be traced back to 1907. 3 In recent years, probiotics have been widely studied by researchers because of their beneficial effects in many aspects. There are many kinds of probiotics, among which Lactobacillus, Bifidobacterium, and Streptococcus and so on are widely used and studied. Probiotics have a wide range of functions. For example, they can maintain the immune balance of gastrointestinal tract, treat gastrointestinal diseases. 4 At the same time, it also has the function of alleviating anxiety, depression, and obesity. 5,6 And beyond that, probiotics cannot be underestimated in the treatment of skin diseases, such as atopic dermatitis, acne, rosacea, psoriasis and so on. [7][8][9] It can treat skin diseases by producing certain cytokine analogs that inhibit the growth of pathogenic bacteria. [10][11][12] Treatment can also be achieved by regulating the immune system and improving the skin barrier. 13,14 Nowadays, there are many probiotic products on the market and they are widely used in the clinic.People's pursuit of beauty never stops. Skin problems such as skin hyperpigmentation, skin wrinkles, skin aging and skin dehydration caused by some external factors or people's own reasons are always puzzling people. There are many reasons for these skin problems, and researchers are constantly developing safe and effective skin-care products to solve these skin problems. Nowadays, many cosmetics are added with chemicals, such as titanium dioxide, which are more or less toxic and may have adverse effects on
