Abstract-Coronary heart disease ranks as the top disease which causes the death in the Egypt. Intravascular (IV) ultrasound imaging is used along with X-ray coronary angiography to detect vessel pathologies. This paper introduces three automated approaches for detection of lumen and media-adventitia borders in IV images. In the first method, a 2D median filter is used to initialize the lumen and media-adventitia contours. The second method uses the Lucy-Richardson method and the 2D median filter to determine the lumen border. Method three is a combination of two methods to combine their advantages. The catheter boundaries were automatically determined. This method shows a higher accuracy and ability to work under artifacts and noisy conditions.