196 ChemInform Abstract The bis(hydroxyethyl)aminomethylfuro(3,2-b)indoles (II) are prepared as shown in the reaction scheme. They have potent inhibitory effects on platelet aggregation. (IR-, NMR-, MS-data).
A new class of 6,13-bis(arylamino)triphenodithiazines has been synthesized by condensing chloranil with arylamines followed by the reaction of the resulting 2,5-bis(arylamino)-3,6-dichloro-1,4-benzoquinones with zinc 2-aminobenzenthiolates (4) in the presence of a base in Methyl Cellosolve. On the other hand, the reaction of 2,5-dianilino-3,6-dichloro-1,4-benzoquinone (3a) with 4 in DMF proceeded unexpectedly to give 7,14-dihydro-6,13-triphenodithiazinequinones by eliminating the anilino groups of 3a.
335ChemInform Abstract Treatment of the furoindole (I) with halides in DMF in the presence of sodium hydride yields the N-substituted derivatives (II). Their analgesic and antiinflammatory activities are tested.
Die aus Chloranil (I) und den Aminen (II) dargestellten Benzochinone (IIIa) reagieren mit entsprechenden Zinkverbindungen des Typs (IV) je nach Reaktionsbedingung entweder zu den purpurroten bis blauen Titelverbindungen (V) bzw. unter Eliminierung der Anilingruppen zu den grünen bis blauen Titelverbindungen (VI).
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