By using mirrors with specially designed transmissions in a diode end-pumped hemispherical cavity, laser oscillations except for 1580 nm were suppressed and an enhanced pulse performance of an acousto-optic Q-switched laser at a single wavelength of 1580 nm was realized for Er:Yb:RAl 3 (BO 3 ) 4 crystals. When the absorbed pump power was 13.5 W and the pulse repetition frequency was 1 kHz, 250 µJ Q-switched pulse energy with a width of 215 ns and 350 µJ Q-switched pulse energy with a width of 125 ns were achieved in Er:Yb:YAl 3 (BO 3 ) 4 and Er:Yb:LuAl 3 (BO 3 ) 4 crystals, respectively. The pulsed laser performances of both the crystals were also compared and investigated in detail.