This study investigated a novel method for artificial synthesis of β-tricalcium phosphate (β-TCP). The binder of the phosphate-bonded investment was replaced with calcium oxide instead of magnesium oxide and sintered in an electric furnace. The water/powder mixing ratio for hardening was determined using preliminary experiments. Thermal analysis was performed to check the thermal behavior of the sample tested. In addition, the fired sample was analyzed using an X-ray diffraction apparatus to identify the compounds after sintering. The hardened sample exhibited multiple compounds, including unreacted components, post which, new compounds were generated by heating. Peaks of calcium pyrophosphate and β-TCP were confirmed at 800ºC and 1,300ºC, respectively. β-TCP could be easily synthesized within the limited study by sintering at 1,300ºC both monoammonium phosphate and calcium oxide. Experimental results suggest that β-TCP can be easily synthesized by simulating the conventional dental casting process.