No abstract

In the present work, a facile approach was employed to fabricate a UV/heat dual-responsive triple shape memory polymer (SMP) by simply mixing Zn(Mebip)2(NTf2)2, a metallosupramolecular unit formed by coordinating 2,6-bis(N-methyl-benzimidazolyl)-pyridine (Mebip) ligands to zinc di[bis(trifluoromethylsulfonyl)-imide] (Zn(NTf2)2), into one part of epoxy resin.

eThe native plasmid of both Chlamydia muridarum and Chlamydia trachomatis has been shown to control virulence and infectivity in mice and in lower primates. We recently described the development of a plasmid-based genetic transformation protocol for Chlamydia trachomatis that for the first time provides a platform for the molecular dissection of the function of the chlamydial plasmid and its individual genes or coding sequences (CDS). In the present study, we transformed a plasmid-free lymphogranuloma venereum isolate of C. trachomatis, serovar L2, with either the original shuttle vector (pGFP::SW2) or a derivative of pGFP::SW2 carrying a deletion of the plasmid CDS5 gene (pCDS5KO). Female mice were inoculated with these strains either intravaginally or transcervically. We found that transformation of the plasmid-free isolate with the intact pGFP::SW2 vector significantly enhanced infectivity and induction of host inflammatory responses compared to the plasmid-free parental isolate. Transformation with pCDS5KO resulted in infection courses and inflammatory responses not significantly different from those observed in mice infected with the plasmid-free isolate. These results indicate a critical role of plasmid CDS5 in in vivo fitness and in induction of inflammatory responses. To our knowledge, these are the first in vivo observations ascribing infectivity and virulence to a specific plasmid gene.

We present an analytical model for jets in Fanaroff & Riley Class I (FR I) radio galaxies, in which an initially laminar, relativistic flow is surrounded by a shear layer. We apply the appropriate conservation laws to constrain the jet parameters, starting the model where the radio emission is observed to brighten abruptly. We assume that the laminar flow fills the jet there and that pressure balance with the surroundings is maintained from that point outwards. Entrainment continuously injects new material into the jet and forms a shear layer, which contains material from both the environment and the laminar core. The shear layer expands rapidly with distance until finally the core disappears, and all of the material is mixed into the shear layer. Beyond this point, the shear layer expands in a cone and decelerates smoothly. We apply our model to the well‐observed FR I source 3C 31 and show that there is a self‐consistent solution. We derive the jet power, together with the variations of mass flux and entrainment rate with distance from the nucleus. The predicted variation of bulk velocity with distance in the outer parts of the jets is in good agreement with model fits to Very Large Array observations. Our prediction for the shape of the laminar core can be tested with higher‐resolution imaging.

We present the discovery and high-cadence follow-up observations of SN2018ivc, an unusual SNe II that exploded in NGC1068 (D=10.1 Mpc). The light curve of SN2018ivc declines piecewise-linearly, changing slope frequently, with four clear slope changes in the first 30 days of evolution. This rapidly changing light curve indicates that interaction between the circumstellar material and ejecta plays a significant role in the evolution. Circumstellar interaction is further supported by a strong X-ray detection. The spectra are rapidly evolving and dominated by hydrogen, helium, and calcium emission lines. We identify a rare high-velocity emission-line feature blueshifted at ∼7800 km s 1 (in Hα, Hβ, Pβ, Pγ, He I, and Ca II), which is visible from day 18 until at least day 78 and could be evidence of an asymmetric progenitor or explosion. From the overall similarity between SN2018ivc and SN1996al, the Hα equivalent width of its parent H IIregion, and constraints from pre-explosion archival Hubble Space Telescope images, we find that the progenitor of SN2018ivc could be as massive as 52 M  but is more likely <12 M . SN2018ivc demonstrates the importance of the early discovery and rapid follow-up observations of nearby supernovae to study the physics and progenitors of these cosmic explosions.