Aim: We aimed to evaluate the clinical and radiological follow-up of cases with isolated linear fractures detected in the cranium in the post-traumatic period, to determine on which cases and when to perform control radiological examinations and to suggest follow-up protocol. Material and Method: 442 cases with isolated linear cranium fracture were evaluated in the study. Imaging examinations and clinical findings of the cases at the time of admission were compared with radiological examinations and clinical findings at follow-up. Fracture localizations and trauma types were compared. Accompanying maxillofacial fractures depending on the localization of fractures detected in the cranium were determined. Results: In the follow-up CT examinations of 18 out of 442 cases, cerebral contusion in 12 cases and epidural hematoma in 1 case, not detected during initial admission were found. Post-traumatic epilepsy was observed in 4 cases without radiologic findings. In cases receiving follow-up radiological examinations, no significant difference was found between radiological examinations performed during 4-6 hours versus 12-24 hours after trauma. Discussion: Isolated linear fracture cases do not require neurosurgical intervention. The treatment protocol may change depending on findings during the follow-up period. Performing routine follow-up radiological examinations is not cost-effective in cases in which no additional finding is present, and symptoms do not persist.

Introduction and Objective: In COVID-19, sudden onset anosmia-ageusia can be observed in patients, regardless of other rhinologic symptoms or prominent nasal symptoms. In our clinical follow-ups, it has drawn our attention that patients presenting with anosmia-ageusia have milder pulmonary symptoms and milder progression. It was thought that this group of patients were infected with neurosensitive SARS-CoV-2 and the study was planned based on this hypothesis. We present our results to contribute to the literature because our study may be a practical screening approach in patient follow-up, may provide predictions of disease progression, and isolation period can be determined. Materials and Methods: The study was conducted in March 2020, by interviewing recorded patients via phone. Patients’ anosmia-ageusia characteristics, hospitalizations, and recorded Thoracic Computed Tomography (CT) reports were evaluated. The reports were analyzed by a single physician and CT positivity was reported and grouped as mild, moderate and severe. Results: A total of 1438 patients were included in the study. Of the patients, 47.8% were male and 52.0% were male, while the mean age was 44.33 ∓ 16.01 years. In terms of educational levels, patients were found to be elementary (25.6%) and high school (20.7%) graduates at most. Discussion and Conclusion: Hospitalization rates of patients presenting with anosmia-ageusia were lower and their disease progression were milder. We suggest that there are mainly neuro- or pulmonary-sensitive variants of the virus. This characteristic is of great importance for the long-term follow-up of these patients and predictions of complications. Patients presenting with a sudden development of anosmia-ageusia should be considered as positive patients. Quarantine and isolation periods should be extended in these patients, keeping in mind the prolonged RT-PCR positivity as well. Besides, it should be noted that these patients are more likely to develop central nervous system complications and they should be followed up.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can potentially infect female reproductive organs. In this study, we investigated the presence of SARS-CoV-2 in cervicovaginal fluid. This study included 31 female patients aged 18–65 years. The presence of SARS-CoV-2 RNA was investigated by RT‒PCR in two separate cervicovaginal swab samples collected from patients 14 days apart. Viral RNA was extracted using Bio-Speedy ®vNAT® Viral Nucleic Acid Buffer (vNAT) solution, and SARS-CoV-2 RNA was analyzed using Bio-Speedy SARS-CoV-2 RT‒qPCR kits in a Bio-Rad CFX96 TouchTM device. First and second cervical swab samples were collected 14 days apart. The SARS-CoV-2 RNA result was negative in all 53 cervicovaginal swab samples collected. Negative SARS-CoV-2 RNA results in cervicovaginal swab samples indicate that coronavirus disease 2019 (COVID-19) is not sexually transmitted. However, the number of studies on this subject and the sample size examined are still insufficient for reaching this conclusion.