We performed a meta-analysis to evaluate the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery. A systematic literature search up to October 2021 was done and 12 studies included 3555 subjects with closed incisions in orthopaedic trauma surgery at the start of the study: 1833 of them were provided with negative pressure wound therapy and 1722 were conventional wound dressings. They were reporting relationships about the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery. We calculated the odds ratio (OR) and mean difference (MD) with 95% confidence intervals (CIs) to assess the effect of negative pressure wound therapy compared with conventional wound dressings on closed incisions in orthopaedic trauma surgery using the dichotomous and continuous methods with a random or fixed-effect model. Negative pressure wound therapy had significantly lower deep surgical site infection (OR, 0.65; 95% CI, 0.48-0.88, P = .005), superficial surgical site infection (OR, 0.23; 95% CI, 0.11-0.49, P = .31), and wound dehiscence (OR, 0.41; 95% CI, 0.21-0.80, P = .009) compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. However, negative pressure wound therapy had no significant effect on the length of hospital stay (MD, 0.29; 95% CI, À2.00-2.58, P = .80) compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery. Negative pressure wound therapy had significantly lower deep surgical site infection, superficial surgical site infection, and wound dehiscence; however, negative pressure wound therapy had no beneficial effect on the length of hospital stay compared with conventional wound dressings in subjects with closed incisions in orthopaedic trauma surgery.Further studies are required to validate these findings.Weiwei Xie and Lingyan Dai contributed equally to this study.

Objective: To study the diagnostic accuracy of microprobe endoscopic ultrasonography (mEUS) in the diagnosis of bulge of digestive tract, and to summarize and explore the characteristics of ultrasound images of gastrointestinal bulge in mEUS diagnosis, to comprehensively evaluate microprobe ultrasound. The ability of endoscope to diagnose gastrointestinal bulging lesions provides a certain clinical basis for later nursing. Methods: A retrospective analysis of 302 cases of gastrointestinal bulging cases underwent microprobe ultrasound endoscopy from November 2011 to December 2015. The diagnosis of all cases was confirmed by endoscopic pathology, surgical pathology or follow-up. Microprobes were compared. The diagnostic accuracy of the results of ultrasound endoscopy and traditional endoscopy. Results: A total of 302 patients underwent microprobe ultrasound endoscopy, including 274 upper gastrointestinal tract, 28 colorectal, 97 esophagi in upper gastrointestinal tract, 152 in stomach and 25 in duodenum. The coincidence rate of mEUS diagnosis of esophageal bulge lesions was 97.93% (95/97), and the coincidence rate of gastroscopy diagnosis was 68.04 (66/97). The coincidence rate of mEUS diagnosis in gastric elevated lesions was 94.07% (143/152), and the coincidence rate of gastroscopy diagnosis was 50.65% (77/152). Conclusion: Microprobe endoscopic ultrasound can clearly show the structure of each layer of the digestive tract wall, reflecting the origin of the lesion and the depth of infiltration. Therefore, it can make accurate diagnosis of most gastrointestinal bulging lesions.