All inorganic CsPbX3 (X = Cl, Br, I) perovskite nanocrystals (PNCs) with 50-85% photoluminescence quantum yields and tunable emission in the range of 440-682 nm have been successfully synthesized at room temperature in open air. This facile strategy enables us to prepare gram-scale CsPbBr3 NCs with a PLQY approaching 80%.
We
developed a versatile and environmentally friendly solution approach
for the fabrication of a variety of metal sulfide nanocrystal thin
films. Metal oxides, metal hydroxides, metal chlorides, metal acetates,
and metal acetylacetonates can be used as the starting materials and
dissolved in thioglycolic acid and ethanolamine, forming many types
of metal–organic precursor solutions. High quality CdS, SnS,
CuInS2, CuSbS2, Cu2ZnSnS4, Cu(In0.7Ga0.3)S2, and luminescent
Ag-doped Zn
x
Cd1–x
S nanocrystal thin films have been successfully prepared by
spin-coating their corresponding metal precursor solutions. Cu2ZnSn(S,Se)4 thin film solar cell with a power conversion
efficiency of 6.83% has been realized by this versatile method.
IntroductionLate-life depression (LLD) is a common and disabling disorder, which is typically defined as depression in individuals older than 60 years. Estimates of the prevalence of clinically relevant depressive symptoms in older adults typically range from 10% to 15%, and rates of major depression range from 1% to 5%.1-3 Late-life depression is characterized by diverse etiological factors that remain poorly understood.4,5 Successes in delineating the neurobiology of LLD have closely paralleled progress in neuroimaging and have provided evidence that LLD is associated with underlying brain anatomic and functional abnormalities. Structural neuroimaging findings have revealed grey matter volume reductions in multiple fronto-striatal-limbic regions of older depressed patients, including the anterior cingulate cortex (ACC), the prefrontal cortices, the striatum, the hippocampus and the amygdala, 4,6,7 and these regions are The aim of the present study was to conduct a meta-analysis that integrated the reported VBM studies, to determine consistent grey matter alterations in individuals with LLD. Methods: A systematic search was conducted to identify VBM studies that compared patients with LLD and healthy controls. We performed a meta-analysis using the effect size signed differential mapping method to quantitatively estimate regional grey matter abnormalities in patients with LLD. Results: We included 9 studies with 11 data sets comprising 292 patients with LLD and 278 healthy controls in our meta-analysis. The pooled and subgroup meta-analyses showed robust grey matter reductions in the right lentiform nucleus extending into the parahippocampus, the hippocampus and the amygdala, the bilateral medial frontal gyrus and the right subcallosal gyrus as well as a grey matter increase in the right lingual gyrus. Meta-regression analyses showed that mean age and the percentage of female patients with LLD were not significantly related to grey matter changes. Limitations: The analysis techniques, patient characteristics and clinical variables of the studies included were heterogeneous, and most participants were medicated. Conclusion: The present meta-analysis is, to our knowledge, the first to overcome previous inconsistencies in the VBM studies of LLD and provide robust evidence for grey matter alterations within fronto-striatal-limbic networks, thereby implicating them in the pathophysiology of LLD. The mean age and the percentage of female patients with LLD did not appear to have a measurable impact on grey matter changes, although we cannot rule out the contributory effects of medication.
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