No abstract

C sp 3 −N coupling between aliphatic carboxylic acids and Nheterocycles via electrochemical decarboxylation is reported. Various Nalkylation products are successfully obtained in moderate to good yields in the presence of CF 3 SO 2 Na at a constant current in CH 3 CN under ambient conditions. With the help of the Co(OAc) 2 •4H 2 O catalyst, this electrochemical synthesis exhibits satisfying functional-group tolerance for both primary and secondary carboxylic acids that has not been applicable in previous works.

With the help of the photothermal effect of gold nanoparticles (AuNPs), the hydration of the arylacetylenes to synthesize carbonyl compounds is successfully achieved. The reaction proceeds smoothly for various substrates and the ketone products are obtained in good isolated yields up to 91%. The successful gram-scale and sunlight-exposure experiments illustrate the potential application of this method in the future organic syntheses.