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New benzofuranyl‐1,3‐benzoxazines and 1,3‐benzoxazin‐2‐ones are synthesized in which benzofuran is coupled with 1,3‐benzoxazines and 1,3‐benzoxazin‐2‐ones through ‐CONH‐ and ‐COCH2‐ bridges, respectively. The antimicrobial activity of these compounds is reported.

We have accomplished the goal of converting a natural Aribonucleoside into an entity whose structure more closely resembles, in the periphery, that of a different natural A-ribonucleoside, for example, guanosine (1) into a product that bears a peripheral resemblance to adenosine, as in 2. Best results were