As an important worldwide medical issue, bone defect exhibits a variety of physical and psychological consequences on sufferers. Some features of clinical treatments including bone grafting and limb shortening are not satisfactory. Recently, bone tissue engineering has been considered as the most effective approach to dealing with the issue of bone deformities. Meanwhile, a variety of biomaterials have been rationally designed and created for the bone regeneration and tissue repairing. Among all these admirable biomaterials for bone remodeling, zeolite-based materials can serve as efficient scaffold candidates with excellent osteo-inductivity. In addition, the porous nature and high biocompatibility of zeolites endow them with the ability as ideal substrates for cell adhesion and proliferation. More importantly, zeolites are investigated as potential coating materials for implants because they have been proven to increase osteo-conductivity and aid in local elastic modeling. Last but not least, zeolites can also be used to treat bone disorders and act as dietary supplements during the practical applications. Accordingly, numerous benefits of zeolite prompt us to summarize their recent biomedical progress including but not limited to the distinguishing characteristics, broad classifications, as well as promising usages in bone tissue engineering.
As one of the first studies to explore the joint consumption of both leisure and pandemic-related tourism products in former pandemic epicenters, this research expands the scope of dark tourism to include former pandemic epicenters. The motivational determinants of intention to visit leisure and pandemic-related sites are empirically identified using an ordered logit model. This is the first study which formally proposes patriotism as a new push motive in stimulating people to visit post-disaster destinations. The identified segmentations of tourists with different levels of push–pull motives and socio-demographic features provide key stakeholders and practitioners in former epicenters with a systematic recovery plan in the post-pandemic era.
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