The possible role of air-sea latent heat flux (LHF) in tropical cyclone (TC) genesis over the western North Pacific (WNP) is investigated using state-of-the-art satellite and analysis datasets. The authors conducted composite analyses of several meteorological variables after identifying developing and non-developing tropical disturbances from June to October of the period 2000 to 2009. Compared to the non-developing disturbances, increased LHF underlying the developing disturbances enhances boundary-layer specific humidity. The secondary circulation then transports more boundary-layer moisture inward and upward and, thus, induces a stronger moist core in the middle troposphere. Accordingly, the air in the core region ascends following a warmer moist adiabat than that in the environment and results in a stronger upper-level warm core, which is associated with a stronger near-surface tangential wind based on the thermal wind balance. This enlarges the magnitude and negative radial gradient of LHF and, thereby, further increases boundary-layer specific humidity. A tropical depression forms when the near-surface tangential wind increases to a certain extent as a result of the continuing positive feedback between near-surface wind and LHF. The results suggest an important role of wind-driven LHF in TC genesis over the WNP.