The revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar). Br J Addict 1989;84:1353-7. 4.Bostwick JM, Lapid MI. False positives on the clinical institute withdrawal assessment for alcohol-revised: Is this scale appropriate for use in the medically ill? Psychosomatics 2004;45:256-61. 5.Rosenbaum M. Change diagnosis to "alcohol withdrawal delirium"? Am J Psychiatry 2003;160:1357-8.

In this work, we present the first comprehensive molecular field analysis of patent structures on how the chemical structure of drugs impacts the biological binding. This task was formulated as searching for drug structures to reveal shared effects of substitutions across a common scaffold and the chemical features that may be responsible. We used the SureChEMBL patent database, which provides search of the patent literature using keyword-based functionality, as a query engine. The extraction of data of the BK Ca channel openers and aligning them for molecular field similarity with newly designed structures did provide a probable validation method with accurate values. Therefore, in an attempt to increase the true positives, we report a procedure that functions on a multiple analyses modeled on molecular field similarity and common sub-structural search with consensus scoring and high confidence values to obtain greater accuracy during conventional virtual screening.

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